Protein Alignment Mkk4 and sek-4

DIOPT Version :9

• Sequence 1: NP_001163551.1
• Gene: Mkk4 / 41020
• FlyBaseID: FBgn0024326
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_508915.3
• Gene: sek-4 / 180811
• WormBaseID: WBGene00018035
• Length: 364
• Species: Caenorhabditis elegans
• Alignment Length: 359
• Identity: 111/359 - (30%)
• Similarity: 171/359 - (47%)
• Gaps: 43/359 - (11%)

  Fly    62 FGAQ--QPQQTPPVASSQVPPVPAASSSSAADRHRERIRQQACGKLQFGEGGANTHTFTSDDLED 124
            ||.:  :|:...|.....:|.|               ::..|.|.:..  .|.|.:. ..|.|..
 Worm     4 FGRRVPRPKLDLPALRETIPEV---------------LKNGALGYICL--SGRNLNV-PEDMLHG 50

  Fly   125 EGEIGRG-AFGAVNKMTFKKLDKVMAVK----RIRSTVDEKEQKQL----LMDLEVVMKSNECIY 180
            ...||.| ...||.::.:..:  |:|.|    |:....||....:|    |.::.|:.....|.:
 Worm    51 GVRIGSGEGQSAVYRLIYNGM--VIARKDVAVRLPQGGDEDSTNKLMAKRLREVNVINGCAPCPF 113

  Fly   181 IVQFYG-ALFKEGDC---WICMELMDTSLDKFYKYIYEKQQRHIPESILAKITVATVNALNYLKE 241
            ||.|:| .:.|..||   .|.||.|..|.....|.:. |:...:||.::.:|..:.::|:.:|||
 Worm   114 IVHFFGYYVHKYKDCVKIHIFMEEMALSASVLKKEVL-KRGGIVPEFVIGRIACSVIHAMWFLKE 177

  Fly   242 ELKIIHRDVKPSNILLHRRGDIKLCDFGISGQLVDSIAKTKDAGCRPYMAPE--RIDPERAKGYD 304
            :::|||||:||.|||:...|.:|:|||||||.|.|||| ....||:.|.|||  .:....:.||.
 Worm   178 KMQIIHRDIKPGNILIDYDGRVKICDFGISGILQDSIA-VSATGCQQYTAPEINELAMVHSPGYS 241

  Fly   305 VRSDVWSLGITLMEVATGNFPYRKWDSVFEQLCQVVQGEPPRLLTSYNGMEFSKEFVDFVNTCLI 369
            ::||:||||||:.|:||..:||....|.|.....::....|.|   ..|: :|...|:||...|.
 Worm   242 IKSDIWSLGITIFELATLTYPYPVGISEFTLSSTIMTSPAPSL---ERGI-YSDSLVEFVERLLQ 302

  Fly   370 KKESDRPKYSRLLEMPFIRRGETSHTDVAVYVAD 403
            |.:.|||....:.|:.|..:.:...:.:...|.|
 Worm   303 KNKDDRPSIVAVQELKFFVKNDIPFSCIGTGVGD 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mkk4	NP_001163551.1	PKc_MKK4	115..405	CDD:270790	101/304 (33%)
		S_TKc	123..387	CDD:214567	96/278 (35%)
sek-4	NP_508915.3	PKc_like	57..324	CDD:389743	95/274 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	2	1.870