Protein Alignment Mkk4 and sek-3

DIOPT Version :9

• Sequence 1: NP_001163551.1
• Gene: Mkk4 / 41020
• FlyBaseID: FBgn0024326
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_741776.1
• Gene: sek-3 / 180773
• WormBaseID: WBGene00022613
• Length: 411
• Species: Caenorhabditis elegans
• Alignment Length: 399
• Identity: 142/399 - (35%)
• Similarity: 206/399 - (51%)
• Gaps: 61/399 - (15%)

  Fly    18 NPPDQLSLNNLSIRHPPSSTSSTSSGSTSSGSSSSSQHNHVTRCFGAQQPQQTPPVASSQVPPVP 82
            :||.:   ...|.::...|::...||...|.||...|         .|||         .:|...
 Worm     2 DPPKK---RKASPQNVVKSSACKQSGVRQSTSSRKRQ---------LQQP---------AMPDAN 45

  Fly    83 AASSSSAADRHRERIRQQACGKLQFGEGG-----------------ANT---------HTFTSDD 121
            ..:.:.|..|:|..:.:.....::..|..                 :||         |.|..|.
 Worm    46 GHTYAFAPPRNRHNLAKLNLSGMRNPEPDLTNEDNMNSLDYVKKYLSNTLVLPPNDRIHEFERDH 110

  Fly   122 LEDEGEIGRGAFGAVNKMTFKKLDKVMAVKRIRSTVD-------EKEQKQLLMDLEVVMKSNECI 179
            |::...:|.|:||.|.||..:..:..||||:| |.::       .|..::..:::|....::.|.
 Worm   111 LQELELLGNGSFGVVRKMLHRPSNVEMAVKQI-SLINNGPDDAFNKSMQRFRLEVEATKAASNCD 174

  Fly   180 YIVQFYGALFKEGDCWICMELMDTSLDKFYKYIYEKQQRHIPESILAKITVATVNALNYLKEELK 244
            .||::||..|.||..|:||||||.||||.|...::.|:..|||.||..:.|||:.||.:||....
 Worm   175 EIVRYYGITFNEGVAWMCMELMDLSLDKLYMIAHDIQKVEIPEQILGAVAVATIRALEHLKTTHH 239

  Fly   245 IIHRDVKPSNILLHRRGDIKLCDFGISGQLVDSIAKTKDAGCRPYMAPERIDPERAKGYDVRSDV 309
            |||||:|||||||.|.|.:|||||||.|.|.:|:|::.|.||||||||||:.| ...|||::|:|
 Worm   240 IIHRDIKPSNILLDRHGCVKLCDFGICGYLQNSVAQSVDVGCRPYMAPERLAP-NGDGYDIKSEV 303

  Fly   310 WSLGITLMEVATGNFPYRKW-DS-VFEQLCQVVQGEPPRLLTSYNGMEFSKEFVDFVNTCLIKKE 372
            ||||||::|||.|.:||..: |: :.:|:..||.|:||.|.:.:   |.|.....|:..|.||..
 Worm   304 WSLGITMVEVANGKYPYDGFMDAPILDQVRMVVYGDPPILDSDH---EVSMSMKRFIALCTIKDR 365

  Fly   373 SDRPKYSRL 381
            :.|..:..|
 Worm   366 NLRASFDDL 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mkk4	NP_001163551.1	PKc_MKK4	115..405	CDD:270790	122/276 (44%)
		S_TKc	123..387	CDD:214567	118/268 (44%)
sek-3	NP_741776.1	PKc_like	104..393	CDD:389743	122/276 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG51923
OrthoDB	1	1.010	-	-		D470057at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.930