Protein Alignment Mkk4 and map2k2b

DIOPT Version :9

• Sequence 1: NP_001163551.1
• Gene: Mkk4 / 41020
• FlyBaseID: FBgn0024326
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_001121753.1
• Gene: map2k2b / 100002225
• ZFINID: ZDB-GENE-080219-34
• Length: 395
• Species: Danio rerio
• Alignment Length: 413
• Identity: 139/413 - (33%)
• Similarity: 206/413 - (49%)
• Gaps: 83/413 - (20%)

  Fly    67 PQQTP-PV-------ASSQVPPVPAASSSSAA------------DRHRERIRQQACGKLQFGEGG 111
            |::.| |:       |.:...|:.|||.::..            ::.::|:......|...||
Zfish     3 PKKRPDPIVITGSGEAQTTSTPIDAASEANLEALQKKLDELDLDEQQKKRLEAFLTQKANLGE-- 65

  Fly   112 ANTHTFTSDDLEDEGEIGRGAFGAVNKMTFKKLDKVMAVKRIRSTVDEKEQKQLLMDLEVVMKSN 176
                 ...||.:...|:|.|..|.|||:..|....|||.|.|...:....:.|::.:|:|:.:.|
Zfish    66 -----LKDDDFQHICELGAGNGGVVNKVCHKPSGLVMARKLIHLEIKPAIRHQIIRELQVLHECN 125

  Fly   177 ECIYIVQFYGALFKEGDCWICMELMD-TSLDKFYKYIYEKQQRHIPESILAKITVATVNALNYLK 240
            . .|||.||||.:.:|:..||||.|| .|||:..     |:.|.|||.||.|:::|.:..|.||:
Zfish   126 S-PYIVGFYGAFYSDGEISICMENMDGGSLDQVL-----KEARRIPEEILGKVSIAVLRGLAYLR 184

  Fly   241 EELKIIHRDVKPSNILLHRRGDIKLCDFGISGQLVDSIAKTKDAGCRPYMAPERIDPERAKGYDV 305
            |:.:||||||||||||::.||:|||||||:||||:||:|.: ..|.|.||:|||:   :...|.|
Zfish   185 EKHQIIHRDVKPSNILVNCRGEIKLCDFGVSGQLIDSMANS-FVGTRSYMSPERL---QGTHYSV 245

  Fly   306 RSDVWSLGITLMEVATGNFPYRKWD---------------------------------------- 330
            :|||||:|::|:|:|.|.:|....|
Zfish   246 QSDVWSMGLSLVELAIGRYPIPPPDAKELEGIFGRALMDVGEAETHSTSPRPRPPGRPISGHGPV 310

  Fly   331 -SVFEQLCQVVQGEPPRLLTSYNGMEFSKEFVDFVNTCLIKKESDRPKYSRLLEMPFIRRGETSH 394
             ::||.|..:|...||:|   .:|: |:.:|.|||..||||..:||.....|:...||:|.|...
Zfish   311 MAIFELLDYIVNEPPPKL---PHGV-FTPDFQDFVTNCLIKNPADRADLKMLMNHTFIKRAEVEE 371

  Fly   395 TDVAVYVADILESMEKDGITQFT 417
            .|.|.::...:...:....||.|
Zfish   372 MDFAGWLCKTMGLNQPSTPTQTT 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mkk4	NP_001163551.1	PKc_MKK4	115..405	CDD:270790	124/331 (37%)
		S_TKc	123..387	CDD:214567	116/305 (38%)
map2k2b	NP_001121753.1	PKc_MEK	69..382	CDD:132946	124/326 (38%)
		S_TKc	71..364	CDD:214567	116/306 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D688282at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920