Protein Alignment Cyp313b1 and ERG5

DIOPT Version :10

• Sequence 1: NP_649807.1
• Gene: Cyp313b1 / 41019
• FlyBaseID: FBgn0037601
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_013728.1
• Gene: ERG5 / 855029
• SGDID: S000004617
• Length: 538
• Species: Saccharomyces cerevisiae
• Alignment Length: 528
• Identity: 103/528 - (19%)
• Similarity: 187/528 - (35%)
• Gaps: 163/528 - (30%)

  Fly    11 LLLAWLYFLWSRRRYYKVAWQL-RGPIG------WPLIGMGLQMMNPETFLQYMDGLSRQFKAPF 68
            :||.|          .:||:|: :|.|.      ||:||         .||:.:|....::||.:
Yeast    55 ILLVW----------DQVAYQIKKGSIAGPKFKFWPIIG---------PFLESLDPKFEEYKAKW 100

  Fly    69 ISWMGTSC------FLYINDPHSV-EQILNSTHCTNKGDFYRFMSSAIGDGLFTSSSP-RW---- 121
            .|. ..||      |:.|.....: .:||.|:         :|:...:.|.......| .|
Yeast   101 ASG-PLSCVSIFHKFVVIASTRDLARKILQSS---------KFVKPCVVDVAVKILRPCNWVFLD 155

  Fly   122 ---H-KHRRLINPAFGRQILSNFLPIFNAEAEVLLQKLELEGVQHGKR---------LEIYQILK 173
               | .:|:.:|..|.:|.|:.:||    ..|.::.|...:.|:..|.         .|:.:||.
Yeast   156 GKAHTDYRKSLNGLFTKQALAQYLP----SLEQIMDKYMDKFVRLSKENNYEPQVFFHEMREILC 216

  Fly   174 KIVLEAACQTTMGKKMNFQHDGSLCIFKAYNGLTEVCVKRMLSPWL----------YPDLI-YRR 227
            .:.|.:.|.                     |.:||..|:::...:.          :|.:| |.:
Yeast   217 ALSLNSFCG---------------------NYITEDQVRKIADDYYLVTAALELVNFPIIIPYTK 260

  Fly   228 SGLFRLQQKVVGILFGFIEQLLEPIVSV----------------VAANSNPDQQR---SEMEMRG 273
            :...:....:...:|....|:.:..::.                .|.|||.|..|   .|...:.
Yeast   261 TWYGKKTADMAMKIFENCAQMAKDHIAAGGKPVCVMDAWCKLMHDAKNSNDDDSRIYHREFTNKE 325

  Fly   274 KSKAIFIEQVREHVERGQLSWQDVRDEANVTIAATFETTSTALYFTILCLAMHPCYQEKLHKE-- 336
            .|:|:|                       ..:.|:.:.:|:...:....:|..|....|:.:|
Yeast   326 ISEAVF-----------------------TFLFASQDASSSLACWLFQIVADRPDVLAKIREEQL 367

  Fly   337 LVTELPPSGDINLEQLQRLEYTEMVINEAMRLFAPVPMVLRSADQDIQLKRGDGEFLIPRGTQIG 401
            .|.....|.::||:.:::::||.|||.|.:|...||.||.....::..:   ...:..|:|..:.
Yeast   368 AVRNNDMSTELNLDLIEKMKYTNMVIKETLRYRPPVLMVPYVVKKNFPV---SPNYTAPKGAMLI 429

  Fly   402 IDIYNMQRDERVWGPLSRTYNPDAHFGLDSPQRHAFA---------FVPFTKGLRMCIGYRYAQM 457
            ..:|....|..|:      .|||...    |:|....         ::.|..|..:|:|..|..:
Yeast   430 PTLYPALHDPEVY------ENPDEFI----PERWVEGSKASEAKKNWLVFGCGPHVCLGQTYVMI 484

  Fly   458 LMKLLLAR 465
            ....||.:
Yeast   485 TFAALLGK 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313b1	NP_649807.1	CYP313-like	66..498	CDD:410680	87/466 (19%)
ERG5	NP_013728.1	CYP61_CYP710	103..522	CDD:410703	85/461 (18%)