DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp313b1 and CYP94D1

DIOPT Version :9

Sequence 1:	NP_001287239.1	Gene:	Cyp313b1 / 41019	FlyBaseID:	FBgn0037601	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_174713.1	Gene:	CYP94D1 / 840356	AraportID:	AT1G34540	Length:	498	Species:	Arabidopsis thaliana

Alignment Length:	508	Identity:	125/508 - (24%)
Similarity:	226/508 - (44%)	Gaps:	87/508 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 WPLIGM--GLQMMNPETFLQY-MDGLSR------QFKAPFISWMGTSCFLYINDPHSVEQILNST 93
            :|::|.  || :.|...||.: ::.|||      .|:.|     |....:...:|.:||.:|.:.
plant    34 YPIVGSFPGL-VNNRHRFLDWTVETLSRCPTQTAIFRRP-----GKQQLIMTANPSNVEYMLKTK 92

  Fly    94 -HCTNKG-DFYRFMSSAIGDGLFTSSSPRWHKHRRLINPAFGRQILSNFLPIFNAEAEV--LLQK 154
             ....|| .|...:...:|.|:|.|....|.|.|:..:..|..:.|.:|: :.|...|:  .|..
plant    93 FESFPKGQQFTSVLEDFLGHGIFNSDGDMWWKQRKTASYEFSTKSLRDFV-MSNVTVEINTRLVP 156

  Fly   155 LELEGVQHGKRLEIYQILKKIVLEAACQTTMGKKMNFQ-------HDGSLCI--FKAYNGLTEVC 210
            :.:|....||.:::..||::...:..|      |:.|.       |||::.:  .:|:.....:.
plant   157 VLVEAATTGKLIDLQDILERFAFDNIC------KLAFNVDCACLGHDGAVGVNFMRAFETAATII 215

  Fly   211 VKRMLSPWLYPDLIYRRSGLFRLQQKV-VGILFGFIEQLLEPIVSVV------AANSNPDQQRSE 268
            .:|..|.         .|..:|:::|: :|     .|::|...::.|      ...:..||.||.
plant   216 SQRFRSV---------ASCAWRIKKKLNIG-----SERVLRESIATVHKFADEIVRNRIDQGRSS 266

  Fly   269 MEMRGKSKAIFIEQVREHVERGQLSWQDVRDEANVTIAATFETTSTALYFTILCLAMHPCYQEKL 333
             :.:....:.||.  :|.:...::    :||.....|.|..:|||:||.:....|:|||..::|:
plant   267 -DHKEDLLSRFIS--KEEMNSPEI----LRDIVISFILAGRDTTSSALSWFFWLLSMHPEVEDKI 324

  Fly   334 HKELVTELPPSGD-----INLEQLQRLEYTEMVINEAMRLFAPVPMVLRSADQDIQLKRGDGEFL 393
            .:||.:....:|.     ...|.|:.:.|....|.|::||:.|||:.::|..:|..|.  ||.|
plant   325 LQELNSIRARTGKRIGEVYGFEHLKMMNYLHAAITESLRLYPPVPVDIKSCAEDNVLP--DGTF- 386

  Fly   394 IPRGTQIGIDIYNMQRDERVWGPLSRTYNPD-------AHFGLDSPQRHAFAFVPFTKGLRMCIG 451
            :.:|..|..:|:.|.|.|.:||.....::|:       ..|..:.|.:    |..|..|.|||:|
plant   387 VGKGWAITYNIFAMGRMESIWGKDCDRFDPERWIDETNGCFRGEDPSK----FPAFHAGPRMCVG 447

  Fly   452 YRYAQMLMKLLLARIFRSY--RISTEARLEELLVKGNISLKLKDYPLCRVERR 502
            ...|.:.||.::|.:...:  .:..:.|.|.||   :::|::|.....||:.|
plant   448 KDMAYIQMKSIVAAVLERFVVEVPGKERPEILL---SMTLRIKGGLFARVQER 497

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313b1	NP_001287239.1	p450	33..474	CDD:299894	116/478 (24%)
CYP94D1	NP_174713.1	CYP86A	64..490	CDD:410687	112/468 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1194
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010