DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp313b1 and CYP86A4

DIOPT Version :9

Sequence 1:	NP_001287239.1	Gene:	Cyp313b1 / 41019	FlyBaseID:	FBgn0037601	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_171666.1	Gene:	CYP86A4 / 839347	AraportID:	AT1G01600	Length:	554	Species:	Arabidopsis thaliana

Alignment Length:	598	Identity:	130/598 - (21%)
Similarity:	226/598 - (37%)	Gaps:	187/598 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLASIILSGWLLLAWLYFLWSRRRYYKVAWQLRGPIGWPLIGMGLQMMNPETFLQYMDGLSRQ-- 63
            ||...|::|       |:||.:|    ::..|:||..|||:|.             :.||..|
plant     7 MLLVAIVTG-------YWLWFKR----ISRWLKGPRVWPLLGS-------------LPGLIEQRD 47

  Fly    64 ---------------------FKAPFIS----WMGTSCFLYINDPHSVEQILNSTHCTN--KGDF 101
                                 |..||::    .:..:|     ||.::|.:| .|...|  ||..
plant    48 RMHEWITENLRACGGTYQTCIFAVPFLAKKQGLVTVTC-----DPKNLEHML-KTRFDNYPKGPT 106

  Fly   102 YR-FMSSAIGDGLFTSSSPRWHKHR---------RLINPAFG----RQILSNFLPIFNAEAEVLL 152
            :: .....:|.|:|.|....|...|         |.:..|.|    |.|...|.||. |.|:
plant   107 WQSVFHDLLGQGIFNSDGDTWLFQRKTAALEFTTRTLRQAMGRWVNRGIKLRFCPIL-ATAQ--- 167

  Fly   153 QKLELEGVQHGKRLEIYQILKKIVLEAACQTTMGKKMNFQHDGSLC--------IFKAYNGLTEV 209
                    .:.:.:::..::.::..:..|....||      |...|        ...|::..||.
plant   168 --------DNAEPVDLQDLILRLTFDNICGLAFGK------DTRTCAPGLPENGFASAFDRATEA 218

  Fly   210 CVKRMLSP--------WLYPDLIYRRSGLFRLQQKVVGILFGFIEQLLEPIVSVVAANSNPDQQR 266
            .::|.:.|        ||         || .|:..:...| |.|::.|..::     |:...:..
plant   219 SLQRFIIPKFMWKLKKWL---------GL-GLEVSLSRSL-GEIDEYLAAVI-----NTRKQELM 267

  Fly   267 SEME--------------MRGKSKAIFIEQVREHVERGQLSWQDVRDEANVTIAATFETTSTALY 317
            |:.|              |..|::: :.:...:||             |...|.|..:|:|.||.
plant   268 SQQESGTHQRHDDLLSRFMMKKTES-YSDTFLQHV-------------ALNFILAGRDTSSVALS 318

  Fly   318 FTILCLAMHPCYQEKLHKELV---------------TELPPSGDINLEQLQRLEYTEMVINEAMR 367
            :....:.|||..::|:.:|:.               ||.|    :..:::.||.|.:..|:|.:|
plant   319 WFFWLITMHPTVEDKIVREICSVLIETRGTDDVASWTEEP----LGFDEIDRLVYLKAAISETLR 379

  Fly   368 LFAPVPMVLRSADQDIQLKRGDGEFLIPRGTQIGIDIYNMQRDERVWGPLSRTYNPDAHFGLDSP 432
            |:..||...:..:.|..|.  ||.| :|.|:.:...||...|.:..||.....:||:...   ||
plant   380 LYPSVPEDSKHVENDDVLP--DGTF-VPAGSSVTYSIYAAGRMKSTWGEDCLEFNPERWI---SP 438

  Fly   433 ------QRHAFAFVPFTKGLRMCIGYRYAQMLMKLLLARIFRSYRISTEA--RLEELLVKGNISL 489
                  ....:.||.|..|.|:|:|...|.:.||.:.|.:...:|::...  ::|:   |.:::|
plant   439 IDGKFINHDQYRFVAFNAGPRICLGKDLAYLQMKTIAAAVLLRHRLTVVPGHKVEQ---KMSLTL 500

  Fly   490 KLKDYPLCRVERR 502
            .:|:..|..:.:|
plant   501 FMKNGLLVNLYKR 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313b1	NP_001287239.1	p450	33..474	CDD:299894	115/534 (22%)
CYP86A4	NP_171666.1	PLN03195	5..513	CDD:215627	129/596 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1194
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010