DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp313b1 and CYP72A14

DIOPT Version :9

Sequence 1:	NP_001287239.1	Gene:	Cyp313b1 / 41019	FlyBaseID:	FBgn0037601	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_188086.1	Gene:	CYP72A14 / 820696	AraportID:	AT3G14680	Length:	512	Species:	Arabidopsis thaliana

Alignment Length:	515	Identity:	121/515 - (23%)
Similarity:	225/515 - (43%)	Gaps:	83/515 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LASIILSGWL--LLAWLYFL-----WSRRRYYKVAWQLRGPIGWPLIGMGLQMMNPETFLQYMDG 59
            ||.:::|.|:  .|.|::|.     .|.||.     .|.|....||||...:|::     .:::.
plant    12 LAVVVVSWWVWRTLKWVWFTPKMLERSLRRQ-----GLSGTSYTPLIGDFKKMIS-----MFIEA 66

  Fly    60 LSRQFKA-----------PF----------ISWMGTSCFLYINDPHSVEQILNSTHCTNKGDFYR 103
            .|:..|.           |.          ::|.|....:.|.||..::::.|..:...|...:.
plant    67 TSKPIKPTDDITPRVMPHPLQMLKTHGRTNLTWFGPIPTITIMDPEQIKEVFNKVYDFQKAHTFP 131

  Fly   104 FMSSAIGDGLFTSSSPRWHKHRRLINPAFGRQILSNFLPIFNAEAEVLLQKLELEGVQHGK--RL 166
             :|..:|.||.:....:|.:|||:|||||..:.:.|.:.:|:.....|:.:.:......|.  .:
plant   132 -LSKILGTGLVSYDGDKWAQHRRIINPAFHLEKIKNMVHVFHESCSELVGEWDKLVSDKGSSCEV 195

  Fly   167 EIYQILKKIVLEAACQTTMGKKMNFQHDGSLCIFKAYNGLTEVCVKRMLSPWLYPDLIY-RRSGL 230
            :::..|..:..:...:|..|......|.    ||:....|.:: |.:....:..|..|| ...|.
plant   196 DVWPGLTSMTADVISRTAFGSSYREGHR----IFELQAELAQL-VMQAFQKFFIPGYIYLPTKGN 255

  Fly   231 FRLQ---QKVVGILFGFIEQLLEPIVSVVAANSNPDQQRSEMEMRGKSK---AIFIEQVREHVER 289
            .|::   :::..||.|.|.:                ::|:.......|:   .|.:|......|.
plant   256 RRMKTAAREIQDILRGIINK----------------RERARESGEAPSEDLLGILLESNLGQTEG 304

  Fly   290 GQLSWQDVRDEANVTIAATFETTSTALYFTILCLAMHPCYQEKLHKELVTELPPSGDINLEQLQR 354
            ..:|.:|:.:|..:...|..||||..|.:|::.|:.|..:|.:..:| |.::......:.|.|.:
plant   305 NGMSTEDMMEECKLFYLAGQETTSVLLVWTMVLLSQHQDWQARAREE-VKQVFGDKQPDTEGLNQ 368

  Fly   355 LEYTEMVINEAMRLFAPVPMVLRSADQDIQLKRGDGEFLIPRGTQIGIDIYNMQRDERVWGPLSR 419
            |:...|::.|.:||:.||..:.|:..::::|    |:..:|.|.||.:.:..:.||..:||..:.
plant   369 LKVMTMILYEVLRLYPPVVQLTRAIHKEMKL----GDLTLPGGVQISLPVLLVHRDTELWGNDAG 429

  Fly   420 TYNPDAHF--GLDSPQRHAFAFVPFTKGLRMCIGYRY----AQMLMKLLLARIFRSYRIS 473
            .:.|: .|  ||....::..:|.||..|.|:|||..:    |:|.|.|:|.|.  |:.:|
plant   430 EFKPE-RFKDGLSKATKNQVSFFPFAWGPRICIGQNFTLLEAKMAMSLILQRF--SFELS 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313b1	NP_001287239.1	p450	33..474	CDD:299894	110/477 (23%)
CYP72A14	NP_188086.1	p450	24..512	CDD:299894	117/503 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	169	1.000	Domainoid score	I1170
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.960