DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp313b1 and CYP72A11

DIOPT Version :9

Sequence 1:	NP_001287239.1	Gene:	Cyp313b1 / 41019	FlyBaseID:	FBgn0037601	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_188083.1	Gene:	CYP72A11 / 820693	AraportID:	AT3G14650	Length:	512	Species:	Arabidopsis thaliana

Alignment Length:	507	Identity:	117/507 - (23%)
Similarity:	222/507 - (43%)	Gaps:	67/507 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LASIILSGWL--LLAWLYFLWSRRRYYKVAWQLRGPIGWPLIG--------------MGLQMMNP 50
            :|.:::|.|:  .|.|::|.......|.....|.|....||:|              ..:.:.:.
plant    12 VAVVVVSWWVWRTLQWVWFKPKMLESYLRRQGLAGTPYTPLVGDLKKNFSMRAEARSKPINLTDD 76

  Fly    51 ET--FLQYMDGLSRQFKAPFISWMGTSCFLYINDPHSVEQILNSTHCTNKGDFYRFMSSAIGDGL 113
            .|  .:.|...:.:.....|.:|.|....:.|.||..:.::||..:...|...:. :...|..|:
plant    77 ITPRIVPYPLQMLKTHGRTFFTWFGAIPTITIMDPEQITEVLNKVYDFQKAHTFP-LGRLIATGV 140

  Fly   114 FTSSSPRWHKHRRLINPAFGRQILSNFLPIFNAEAEVLLQKLE--LEGVQHGKRLEIYQILKKIV 176
            .:....:|.||||:|||||..:.:.|.:|.|:.....::.|.:  :...:....::::..|..:.
plant   141 LSYDGDKWAKHRRIINPAFHLEKIKNMVPAFHQSCSEIVCKWDKLVSDKESSCEVDVWPGLVSMT 205

  Fly   177 LEAACQTTMGKKMNFQHDGSLC-----IFKAYNGLTEVCVKRMLSPWLYPDLIY-RRSGLFRLQQ 235
            .:...:|..         ||.|     ||:....|.::.::.:...:: |...| ...|..|::.
plant   206 ADVISRTAF---------GSSCVEGQRIFELQAELAQLIIQTVRKAFI-PGYSYLPTKGNRRMKA 260

  Fly   236 K---VVGILFGFIEQLLEPIVSVVAANSNPDQQRSEMEMRGKSKAIFIEQVREHVERGQLSWQDV 297
            |   :..||.|.:.:.|....:..|.|.         ::.|    |.:|......:...:|.:|:
plant   261 KAREIQVILRGIVNKRLRAREAGEAPND---------DLLG----ILLESNLGQTKGNGMSTEDL 312

  Fly   298 RDEANVTIAATFETTSTALYFTILCLAMHPCYQEKLHKELVTELPPSGDINLEQLQRLEYTEMVI 362
            .:|..:......||||..|.:|::.|:.|..:|.:..:| |.::....:.:.|.|.:|:...|::
plant   313 MEECKLFYFVGQETTSVLLVWTMVLLSQHQDWQARAREE-VKQVFGDKEPDAEGLNQLKVMTMIL 376

  Fly   363 NEAMRLFAPVPMVLRSADQDIQLKRGDGEFLIPRGTQIGIDIYNMQRDERVWGPLSRTYNPDAHF 427
            .|.:||:.|:|.:.|:..::::|    |:..:|.|..|.:.|..:|||..:||..:..:.|| .|
plant   377 YEVLRLYPPIPQLSRAIHKEMEL----GDLTLPGGVLINLPILLVQRDTELWGNDAGEFKPD-RF 436

  Fly   428 --GLDSPQRHAFAFVPFTKGLRMCIGYRY----AQMLMKLLLARIFRSYRIS 473
              ||....::..:|.||..|.|:|||..:    |:|.|.|:|.|.  |:.:|
plant   437 KDGLSKATKNQASFFPFAWGSRICIGQNFALLEAKMAMALILQRF--SFELS 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313b1	NP_001287239.1	p450	33..474	CDD:299894	109/474 (23%)
CYP72A11	NP_188083.1	p450	24..512	CDD:299894	114/495 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	169	1.000	Domainoid score	I1170
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.960