DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp313b1 and CYP72A9

DIOPT Version :9

Sequence 1:	NP_001287239.1	Gene:	Cyp313b1 / 41019	FlyBaseID:	FBgn0037601	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_188081.2	Gene:	CYP72A9 / 820691	AraportID:	AT3G14630	Length:	563	Species:	Arabidopsis thaliana

Alignment Length:	540	Identity:	113/540 - (20%)
Similarity:	214/540 - (39%)	Gaps:	151/540 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 WLLLAWLYFLWSRRRYYKVAWQLRGPIG---WPLIG---MGLQM--------MNP-----ETFLQ 55
            |.:|.|   :|.:.:..:...:.:|.:|   .||:|   ....|        |.|     ...:.
plant    73 WRILEW---VWLKPKMLESYLRRQGLVGTRYTPLVGDVRRSFSMLKEARSKPMKPTDDLISLVMP 134

  Fly    56 YMDGLSRQFKAPFISWMGTSCFLYINDPHSVEQILNSTHCTNKGDFYRF-------MSSAIGDGL 113
            |...:...:...|.:|.|....:.|.:|..::::.|.        ||.|       ::|.:.|||
plant   135 YSFHMLNTYGKTFFTWSGPIPAITIMNPQLIKEVYNK--------FYDFEKTHTFPLTSLLTDGL 191

  Fly   114 FTSSSPRWHKHRRLINPAFGRQILSNFLPIFNAEAEVLLQKLELEGVQHGKRLEIYQILKKIVLE 178
            ..:...:|.|||::|||||..:.:.|.:|.|                            .|..:|
plant   192 ANADGDKWVKHRKIINPAFHFEKIKNMVPTF----------------------------YKSCIE 228

  Fly   179 AACQTTMGKKMNFQHDGSLCIFKAYNGLTEVCVKRMLSPWLY---PDLIYR-------RSG--LF 231
            ..|:   .:|: ....||.|....:             ||:.   .|:|.|       :.|  :|
plant   229 VMCE---WEKL-VSDKGSSCELDVW-------------PWIVNMTGDVISRTAFGSSYKEGQRIF 276

  Fly   232 RLQQKVVGILFGFIEQLLEPIVSVVAANSN--------PDQQRSEMEMRGKSKAIFIEQVREHVE 288
            .||.::..::             ::|...|        |.:....|:...|...:.:..:..|.|
plant   277 ILQAELAHLI-------------ILALGKNYIPAYRHFPTKNNRRMKTIVKEIQVILRGIISHRE 328

  Fly   289 RGQ--------------------------LSWQDVRDEANVTIAATFETTSTALYFTILCLAMHP 327
            :.:                          |:.:::.:|..:...|..||||..|.:|::.|:.|.
plant   329 KARDAGEAPSDDLLGILLKSNSEQSKGNGLNMEEIMEECKLFYFAGQETTSVLLAWTMVLLSQHQ 393

  Fly   328 CYQEKLHKELVTELPPSGDINLEQLQRLEYTEMVINEAMRLFAPVPMVLRSADQDIQLKRGDGEF 392
            .:|.:..:| |.::......:|:.:.:|:...|:|.|.:||:.||..:.|:..::|:|    |:.
plant   394 DWQARAREE-VMQVFGHNKPDLQGINQLKVMTMIIYEVLRLYPPVIQMNRATHKEIKL----GDM 453

  Fly   393 LIPRGTQIGIDIYNMQRDERVWGPLSRTYNPDAHF--GLDSPQRHAFAFVPFTKGLRMCIGYRYA 455
            .:|.|.|:.:.:..:.||.::||..:..:.|: .|  |:....::...|:||..|.|:|||..:|
plant   454 TLPGGIQVHMPVLLIHRDTKLWGDDAAEFKPE-RFKDGIAKATKNQVCFLPFGWGPRICIGQNFA 517

  Fly   456 QMLMKLLLARIFR--SYRIS 473
            .:..|:.||.|.:  |:.:|
plant   518 LLEAKMALALILQRFSFELS 537

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313b1	NP_001287239.1	p450	33..474	CDD:299894	109/517 (21%)
CYP72A9	NP_188081.2	p450	59..563	CDD:386267	113/540 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	169	1.000	Domainoid score	I1170
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050