DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp313b1 and Cyp4d14

DIOPT Version :9

Sequence 1:	NP_001287239.1	Gene:	Cyp313b1 / 41019	FlyBaseID:	FBgn0037601	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_001259179.1	Gene:	Cyp4d14 / 45706	FlyBaseID:	FBgn0023541	Length:	510	Species:	Drosophila melanogaster

Alignment Length:	503	Identity:	134/503 - (26%)
Similarity:	241/503 - (47%)	Gaps:	59/503 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LASIILSGWLLLAWLYFLWSRRRYYKVAWQ--LRGPIGWPLIGMGLQMMN--PETFLQYMDGLSR 62
            |.:|:|:  ..|||.|.  .:||:.|:..:  :|||..:||:|....::|  |::.....|   .
  Fly     5 LFAILLA--TALAWDYM--RKRRHNKMYAEAGIRGPKSYPLVGNAPLLINESPKSKSSIFD---M 62

  Fly    63 QFK--APF-----ISWMGTSCFLYINDPHSVEQILNSTHCTNKGDFYRFMSSAIGDGLFTSSSPR 120
            ||:  |.|     ...:|.|.|: ..|...:|.|::|.....|.:.|..:.:.:||||..|...:
  Fly    63 QFRLIAEFGKNIKTQMLGESGFM-TADSKMIEAIMSSQQTIQKNNLYSLLVNWLGDGLLISQGKK 126

  Fly   121 WHKHRRLINPAFGRQILSNFLPIFNAEAEVLLQKLELEGVQHGKR-LEIYQILKKIVLEAACQTT 184
            |.:.|::|.|||..:||.:|:.:|:.::..::|||....  .||. :.::.:.....::...:|.
  Fly   127 WFRRRKIITPAFHFKILEDFVEVFDQQSATMVQKLYDRA--DGKTVINMFPVACLCAMDIIAETA 189

  Fly   185 MGKKMNFQHDGSLCIFKAYNGLTEVCVKRMLSP---------WLYPDLIYRRSGLFRLQQKVVGI 240
            ||.|:|.|........::....:.:..:|.::|         ..||.|:.:.:...:........
  Fly   190 MGVKINAQLQPQFTYVQSVTTASAMLAERFMNPLQRLDFTMKLFYPKLLDKLNDAVKNMHDFTNS 254

  Fly   241 LFGFIEQLLEPIVS----VVAANSNPDQQRSEMEMRGKSKAIFIEQVREHVERGQLSWQDVRDEA 301
            :.....:||:..::    ..||..|...|:..|       |:....::..::...||..|:|:|.
  Fly   255 VITERRELLQKAIADGGDADAALLNDVGQKRRM-------ALLDVLLKSTIDGAPLSNDDIREEV 312

  Fly   302 NVTIAATFETTSTALYFTILCLAMHPCYQEKLHKEL--VTELPPSGDINLEQLQRLEYTEMVINE 364
            :..:....:||::::.||...||.||..|.::.:|:  |.....|..:.::.|..|:|.|.||.|
  Fly   313 DTFMFEGHDTTTSSIAFTCYLLARHPEVQARVFQEVRDVIGDDKSAPVTMKLLGELKYLECVIKE 377

  Fly   365 AMRLFAPVPMVLRSADQDIQLKRGDGEFLIPRGTQIGIDIYNMQRDERVWGPLSRTYNPDAHFGL 429
            ::|||..||::.|...||..|   ||: |||..:.:.|.||:.|||...: |....:.|| .|.:
  Fly   378 SLRLFPSVPIIGRYISQDTVL---DGK-LIPADSNVIILIYHAQRDPDYF-PDPEKFIPD-RFSM 436

  Fly   430 D-----SPQRHAFAFVPFTKGLRMCIGYRYAQMLMKLLLARIFRSYRI 472
            :     ||    ||:.||:.|.|.|||.::|.:.||..::::.|.:.:
  Fly   437 ERKGEISP----FAYTPFSAGPRNCIGQKFAMLEMKSTISKMVRHFEL 480

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313b1	NP_001287239.1	p450	33..474	CDD:299894	124/470 (26%)
Cyp4d14	NP_001259179.1	p450	34..489	CDD:278495	124/470 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	101	1.000	Domainoid score	I1781
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
	5	4.970