Protein Alignment Cyp313b1 and CYP4F3

DIOPT Version :10

• Sequence 1: NP_649807.1
• Gene: Cyp313b1 / 41019
• FlyBaseID: FBgn0037601
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_000887.2
• Gene: CYP4F3 / 4051
• HGNCID: 2646
• Length: 520
• Species: Homo sapiens
• Alignment Length: 532
• Identity: 143/532 - (26%)
• Similarity: 245/532 - (46%)
• Gaps: 68/532 - (12%)

  Fly     1 MLASIILSGWLL---LAWLYFLWSRRRYYKVAWQLR-----GPIGWPLIGMGLQMMNPETFLQYM 57
            :|..::.:.|||   |||.|      .:|....:||     ....|.|..:|| :.:.|..|.|.
Human    20 LLLLLVGASWLLARILAWTY------TFYDNCCRLRCFPQPPKRNWFLGHLGL-IHSSEEGLLYT 77

  Fly    58 DGLSRQFKAPFISWMGTSCFLYINDPHSVEQILNSTH-----------CTNKGDFYRFMSSAIGD 111
            ..|:..|        |..|..::...|::.:|.:.|:           ......||.|:...:||
Human    78 QSLACTF--------GDMCCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVFYSFLKPWLGD 134

  Fly   112 GLFTSSSPRWHKHRRLINPAFGRQILSNFLPIFNAEAEVLLQKLELEGVQHGKRLEIYQILKKIV 176
            ||..|:..:|.:|||::.|||...||..::.|||....::..|.:|...:...||::::.:..:.
Human   135 GLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLDMFEHISLMT 199

  Fly   177 LEAACQTTMGKKMNFQHDGSLCIFK------AYNGLTEVCVKRMLSPWLYPDLIYRRSGLFRLQQ 235
            |::.      :|..|..| |.|..|      |...|:.:..||.....||.|.:|..:...:..:
Human   200 LDSL------QKCVFSFD-SHCQEKPSEYIAAILELSALVTKRHQQILLYIDFLYYLTPDGQRFR 257

  Fly   236 KVVGILFGFIEQLLEPIVSVVAANSNPDQQRSE-MEMRGKSKAI-FIE--QVREHVERGQLSWQD 296
            :...::..|.:.:::.     ...:.|.|...: ::.:.|||.: ||:  .:.:..:..:||.:|
Human   258 RACRLVHDFTDAVIQE-----RRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDED 317

  Fly   297 VRDEANVTIAATFETTSTALYFTILCLAMHPCYQEKLH---KELVTELPPSGDINLEQLQRLEYT 358
            :|.||:..:....:||::.|.:.:..||.||.|||:..   :||:.:..|. :|..:.|.:|.:.
Human   318 IRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPK-EIEWDDLAQLPFL 381

  Fly   359 EMVINEAMRLFAPVPMVLRSADQDIQLKRGDGEFLIPRGTQIGIDIYNMQRDERVWGPLSRTYNP 423
            .|.|.|::||..|||.|.|...|||.|.  ||. :||:|....|.::....:..|| |....|:|
Human   382 TMCIKESLRLHPPVPAVSRCCTQDIVLP--DGR-VIPKGIICLISVFGTHHNPAVW-PDPEVYDP 442

  Fly   424 DAHFGLDSPQRHAFAFVPFTKGLRMCIGYRYAQMLMKLLLARIFRSYRI---STEARLE-ELLVK 484
            ......:..:|...||:||:.|.|.|||..:|...||::|......:|:   .||.|.: ||:::
Human   443 FRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLRFRVLPDHTEPRRKPELVLR 507

  Fly   485 GNISLKLKDYPL 496
            ....|.|:..||
Human   508 AEGGLWLRVEPL 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313b1	NP_649807.1	CYP313-like	66..498	CDD:410680	123/459 (27%)
CYP4F3	NP_000887.2	CYP4F	74..515	CDD:410772	124/465 (27%)