DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp313b1 and Cyp4p2

DIOPT Version :9

Sequence 1:	NP_001287239.1	Gene:	Cyp313b1 / 41019	FlyBaseID:	FBgn0037601	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_610472.1	Gene:	Cyp4p2 / 35946	FlyBaseID:	FBgn0033395	Length:	520	Species:	Drosophila melanogaster

Alignment Length:	468	Identity:	108/468 - (23%)
Similarity:	223/468 - (47%)	Gaps:	50/468 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 ETFLQYMDGLSRQFKAPFISWMGTSCFLYINDPHSVEQILNSTHCTNKGDFYRFMSSAIGDGLFT 115
            :::|||.              ||.|.|..| |.|:...|||..:...||..|.|:...:..|:.|
  Fly    84 DSYLQYS--------------MGFSNFNVI-DAHNAANILNHPNLITKGVIYNFLHPFLRTGVLT 133

  Fly   116 SSSPRWHKHRRLINPAFGRQILSNFLPIFNAEAEVLLQKLELEGVQHGKRLEIYQILKKIVLEAA 180
            ::..:||..|.::...|...||:.|..||.||:...:.  :.:| |:...:.:...:.:..|.:.
  Fly   134 ATEKKWHTRRSMLTRTFHLDILNQFQEIFIAESLKFVS--QFQG-QNEVVVSLKDRISRFTLNSI 195

  Fly   181 CQTTMGKKMNFQHDGSLCIFKAYNGLTEVCVKRMLSPWLYPDLIYRR-SG---------LFRLQQ 235
            |:|.||.|::...:........::.:.|...:|:::|..:.|.:|.. :|         :....:
  Fly   196 CETAMGIKLDEMAEKGDRYRANFHIIDEGLTRRIVNPLYWDDCVYNMFTGHKYNAALKVVHEFSR 260

  Fly   236 KVVGILFGFIEQLLEPIVSVVAANSNPDQQRSEMEMRGKSKAIFIEQVREHVERGQLSWQDVRDE 300
            :::......:|:.||...:...|:       .::.:..|.:...::.:....:.|.:....:.:|
  Fly   261 EIIAKRRVLLEEELENRRATQTAD-------DDICVIRKKRFAMLDTLICAEKDGLIDDIGISEE 318

  Fly   301 ANVTIAATFETTSTALYFTILCLAMHP-----CYQEKLHKELVTELPPSGDINLEQLQRLEYTEM 360
            .:..:|..::|||..|.|.::.::::.     |||| :.:.::.:|   .::||.||.:|.|...
  Fly   319 VDTLMAEGYDTTSIGLVFGLMNMSLYAAEQELCYQE-IQEHILDDL---SNLNLSQLSKLNYLGY 379

  Fly   361 VINEAMRLFAPVPMVLRSADQDIQLKRGDGEFLIPRGTQIGIDIYNMQRDERVW-GPLSRTYNPD 424
            .|.|.|||:..:|::.|...|:.:|:.|   .::|:.:||.|.::::.|:.:.| .|  ..:.|:
  Fly   380 FIKETMRLYPSIPIMGRQTLQETELENG---LILPKRSQINIHVFDIHRNPKYWESP--EEFRPE 439

  Fly   425 AHFGLDSPQRHAFAFVPFTKGLRMCIGYRYAQMLMKLLLARIFRSYRISTEARLEELLVKGNISL 489
            .....:..:||.:|::||:.|.|.|||.:||...||.|:..|.:.::|......:.::.:..|:|
  Fly   440 RFLPQNCLKRHPYAYIPFSAGQRNCIGQKYAMQEMKTLMVVILKHFKILPVIDPKSIVFQVGITL 504

  Fly   490 KLKDYPLCRVERR 502
            :.|:....::.||
  Fly   505 RFKNKIKVKLVRR 517

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313b1	NP_001287239.1	p450	33..474	CDD:299894	103/438 (24%)
Cyp4p2	NP_610472.1	p450	63..514	CDD:299894	106/463 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	101	1.000	Domainoid score	I1781
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
	5	4.970