DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp313b1 and Cyp26b1

DIOPT Version :9

Sequence 1:	NP_001287239.1	Gene:	Cyp313b1 / 41019	FlyBaseID:	FBgn0037601	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_851601.2	Gene:	Cyp26b1 / 312495	RGDID:	631379	Length:	512	Species:	Rattus norvegicus

Alignment Length:	519	Identity:	124/519 - (23%)
Similarity:	216/519 - (41%)	Gaps:	107/519 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LASIILSGWLLLAWLYFLWSRRRYYKVAWQL-----------RGPIGWPLI---------GMGLQ 46
            ||:.::|..||||....||..|      |..           :|.:|:|||         |.|.|
  Rat    15 LAACLVSVTLLLAVSQQLWQLR------WAATRDKSCKLPIPKGSMGFPLIGETGHWLLQGSGFQ 73

  Fly    47 MMNPETFLQYMDGLSRQFKA-----PFISWMGTSCFLYINDPHSVEQILNSTHCTNKGDFYRFMS 106
            ....|.:       ...||.     |.|...|.         .:|.:||...|.....::.|...
  Rat    74 SSRREKY-------GNVFKTHLLGRPLIRVTGA---------ENVRKILLGEHQLVSTEWPRSAR 122

  Fly   107 SAIGDGLFTSSSPRWHKH-RRLINPAFGRQILSNFLPIFNAEAEVLLQKLELEGVQHGKRLEIYQ 170
            ..:|.....:|....|:: |::.:..|..:.|.::||    :.::::|..........:.:.:||
  Rat   123 VLLGPNTVANSIGDIHRNKRKVFSKIFSHEALESYLP----KIQLVIQDTLRAWSSQPEAINVYQ 183

  Fly   171 ILKKIVLEAACQTTMGKKMNFQHDGSLCIFKAYNGLTEVCVKRMLS-PWLYPDLIYRRSGLFRLQ 234
            ..:::....|.:..:|..:..:..|:|  |:.|    :..|:.:.| |...|...|||.    :|
  Rat   184 EAQRLTFRMAVRVLLGFSIPEEDLGNL--FEVY----QQFVENVFSLPVDLPFSGYRRG----IQ 238

  Fly   235 QKVVGILFGFIEQLLEPIVSVVAANSNPDQQRSEME-MRGKSKA----IFIEQVREHVERGQLSW 294
            .:.:      :::.||..:            |.::: .:||..:    |.||..:||.:  :::.
  Rat   239 ARQI------LQKGLEKAI------------REKLQCTQGKDYSDALDILIESSKEHGK--EMTM 283

  Fly   295 QDVRDEANVTIAATFETTSTALYFTILCLAMHPCYQEKLHKELVTE-------LPPSGDINLEQL 352
            |:::|.....|.|.:.||::|....|:.|..||...|||.:||..:       .|..|.:.|:.|
  Rat   284 QELKDGTLELIFAAYATTASASTSLIMQLLKHPAVLEKLREELRAQGLLHGGGCPCEGTLRLDML 348

  Fly   353 QRLEYTEMVINEAMRLFAPVPMVLRSADQDIQLKRGDGEFLIPRGTQIGIDIYNMQRDERVWGPL 417
            ..|.|.:.||.|.||||.||....|:..|..:|   || |.||:|..:   :|:: ||.....|:
  Rat   349 SGLRYLDCVIKEVMRLFTPVSGGYRTVLQTFEL---DG-FQIPKGWSV---MYSI-RDTHDTAPV 405

  Fly   418 SR---TYNPDAHFGLDSPQRHA-FAFVPFTKGLRMCIGYRYAQMLMKLLLARIFRSYRISTEAR 477
            .:   .::||......|..:.. |.::||..|:|.|:|...|::.:|:|...:..:.|.....|
  Rat   406 FKDVNVFDPDRFSQARSEDKDGRFHYLPFGGGVRTCLGKHLAKLFLKVLAVELASTSRFELATR 469

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313b1	NP_001287239.1	p450	33..474	CDD:299894	112/472 (24%)
Cyp26b1	NP_851601.2	CYP26B1	60..490	CDD:410730	108/468 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000