DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp313b1 and Cyp4d2

DIOPT Version :9

Sequence 1:	NP_001287239.1	Gene:	Cyp313b1 / 41019	FlyBaseID:	FBgn0037601	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_001284806.1	Gene:	Cyp4d2 / 31192	FlyBaseID:	FBgn0011576	Length:	501	Species:	Drosophila melanogaster

Alignment Length:	475	Identity:	129/475 - (27%)
Similarity:	243/475 - (51%)	Gaps:	32/475 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LLAWLYFLWSRRRYYKVAWQLRGPIGWPLIGMGLQM--MNPETFLQYMDGLSRQFKAPFISWMGT 74
            ||.| .||| |||...:   |.||...|.:|..|..  ::||..:.::....|::...:..|:..
  Fly    16 LLLW-DFLW-RRRGNGI---LPGPRPLPFLGNLLMYRGLDPEQIMDFVKKNQRKYGRLYRVWILH 75

  Fly    75 SCFLYINDPHSVEQILNSTHCTNKGDFYRFMSSAIGDGLFTSSSPRWHKHRRLINPAFGRQILSN 139
            ...::..||..:|.:|:|.....|.:.|:.::..:||||..|:..:||..|::|.|.|..:||..
  Fly    76 QLAVFSTDPRDIEFVLSSQQHITKNNLYKLLNCWLGDGLLMSTGRKWHGRRKIITPTFHFKILEQ 140

  Fly   140 FLPIFNAEAEVLLQKLE--LEGVQHGKRLEIYQILKKIVLEAACQTTMGKKMNFQHDGSLCIFKA 202
            |:.||:.::.|::::|:  .:|:   ..:.|:.::....|:...:|.||.|:|.|.:.:|...:|
  Fly   141 FVEIFDQQSAVMVEQLQSRADGM---TPINIFPVICLTALDIIAETAMGTKINAQKNPNLPYVQA 202

  Fly   203 YNGLTEVCVKRMLSPWLYPDLIYR--RSGLFRLQQKVVGILFGFIEQLLEPIVSVVAANSNPDQQ 265
            .|.:|.:.:||.:..|...|.|:|  :....:.|.|.:.::..|.|.::......:..||.....
  Fly   203 VNDVTNILIKRFIHAWQRVDWIFRLTQPTEAKRQDKAIKVMHDFTENIIRERRETLVNNSKETTP 267

  Fly   266 RSEMEMRGKSKAIFIEQV--REHVERGQLSWQDVRDEANVTIAATFETTSTALYFTILCLAMHPC 328
            ..|:...|:.:.:.:..|  :..::...||.:|:|:|.:..:....:||::|:.|.:..::.||.
  Fly   268 EEEVNFLGQKRRMALLDVLLQSTIDGAPLSDEDIREEVDTFMFEGHDTTTSAISFCLYEISRHPE 332

  Fly   329 YQEKLHKEL--VTELPPSGDINLEQLQRLEYTEMVINEAMRLFAPVPMVLRSADQDIQLKRGDGE 391
            .|::|.:|:  |........:.|..|..|::.|.||.|::||..||||:.|...:|::::   |:
  Fly   333 VQQRLQQEIRDVLGEDRKSPVTLRDLGELKFMENVIKESLRLHPPVPMIGRWFAEDVEIR---GK 394

  Fly   392 FLIPRGTQIGIDIYNMQRDERVWGPLSRTYNPD----AHFGLDSPQRHAFAFVPFTKGLRMCIGY 452
            . ||.||...:.|:.:.||...:      .:||    ..|..|.||.|.:|::||:.|.|.|||.
  Fly   395 H-IPAGTNFTMGIFVLLRDPEYF------ESPDEFRPERFDADVPQIHPYAYIPFSAGPRNCIGQ 452

  Fly   453 RYAQMLMKLLLARIFRSYRI 472
            ::|.:.||..::::.|.:.:
  Fly   453 KFAMLEMKSTVSKLLRHFEL 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313b1	NP_001287239.1	p450	33..474	CDD:299894	119/454 (26%)
Cyp4d2	NP_001284806.1	p450	32..495	CDD:278495	119/454 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	101	1.000	Domainoid score	I1781
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
	5	4.970