Protein Alignment Cyp313b1 and CYP4V2

DIOPT Version :10

• Sequence 1: NP_649807.1
• Gene: Cyp313b1 / 41019
• FlyBaseID: FBgn0037601
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_997235.3
• Gene: CYP4V2 / 285440
• HGNCID: 23198
• Length: 525
• Species: Homo sapiens
• Alignment Length: 539
• Identity: 153/539 - (28%)
• Similarity: 255/539 - (47%)
• Gaps: 69/539 - (12%)

  Fly    10 WLLLAW-LYFLW------------------SRRRYYKVAWQLRGPI-----GWPLIGMGLQMMNP 50
            ||.|.| ...||                  .|...|...||...||     .:||:|..| :|.|
Human     5 WLGLVWQKLLLWGAASALSLAGASLVLSLLQRVASYARKWQQMRPIPTVARAYPLVGHAL-LMKP 68

  Fly    51 ---ETFLQYMDGLSRQFKAPFIS-WMGTSCFLYINDPHSVEQILNSTHCTNKGDFYRFMSSAIGD 111
               |.|.|.::........|.:. |:|....:.:.:..:||.||.|:...:|...|:|:...:|.
Human    69 DGREFFQQIIEYTEEYRHMPLLKLWVGPVPMVALYNAENVEVILTSSKQIDKSSMYKFLEPWLGL 133

  Fly   112 GLFTSSSPRWHKHRRLINPAFGRQILSNFLPIFNAEAEVLLQKLELEGVQHGKRLEIYQILKKIV 176
            ||.||:..:|...|:::.|.|...||.:||.|.|.:|.:|::|||....|.......|..|  ..
Human   134 GLLTSTGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILVKKLEKHINQEAFNCFFYITL--CA 196

  Fly   177 LEAACQTTMGKKMNFQHDGSLCIFKAYNGLTEVCVKRMLSPWLYPDLIYRRSGLFR---LQQKVV 238
            |:..|:|.|||.:..|.:......:|...::|:..:|:..|||:.||.|.   :|:   ..:|.:
Human   197 LDIICETAMGKNIGAQSNDDSEYVRAVYRMSEMIFRRIKMPWLWLDLWYL---MFKEGWEHKKSL 258

  Fly   239 GILFGFIEQLLEPIVSVVA-----ANSNPD---QQRSEMEMRGKSKAIFIEQVREHV--ERGQLS 293
            .||..|..       ||:|     .|:|.|   ..|.....:.|.:| |::.:....  |..:||
Human   259 QILHTFTN-------SVIAERANEMNANEDCRGDGRGSAPSKNKRRA-FLDLLLSVTDDEGNRLS 315

  Fly   294 WQDVRDEANVTIAATFETTSTALYFTILCLAMHPCYQEKLHKEL-----VTELPPSGDINLEQLQ 353
            .:|:|:|.:..:....:||:.|:.:::..|..:|..|:|:..||     .::.|.:    :|.|:
Human   316 HEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQKKVDHELDDVFGKSDRPAT----VEDLK 376

  Fly   354 RLEYTEMVINEAMRLFAPVPMVLRSADQDIQLKRGDGEFLIPRGTQIGIDIYNMQRDERVWGPLS 418
            :|.|.|.||.|.:|||..||:..||..:|.::    ..:.:.:||:..|..|.:.||.|.: |..
Human   377 KLRYLECVIKETLRLFPSVPLFARSVSEDCEV----AGYRVLKGTEAVIIPYALHRDPRYF-PNP 436

  Fly   419 RTYNPDAHFGLDSPQRHAFAFVPFTKGLRMCIGYRYAQMLMKLLLARIFRSYRISTEARLEELLV 483
            ..:.|:..|..::..||.:|:|||:.|.|.|||.::|.|..|.:|:.|.|.:.|.:..:.|||.:
Human   437 EEFQPERFFPENAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRHFWIESNQKREELGL 501

  Fly   484 KGNISLKLKDYPLCRVERR 502
            :|.:.|:..:....:::||
Human   502 EGQLILRPSNGIWIKLKRR 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313b1	NP_649807.1	CYP313-like	66..498	CDD:410680	130/450 (29%)
CYP4V2	NP_997235.3	CYP4V	76..515	CDD:410773	131/460 (28%)