DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp313b1 and Cyp4f6

DIOPT Version :9

Sequence 1:	NP_001287239.1	Gene:	Cyp313b1 / 41019	FlyBaseID:	FBgn0037601	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	XP_006241111.1	Gene:	Cyp4f6 / 266689	RGDID:	708365	Length:	538	Species:	Rattus norvegicus

Alignment Length:	522	Identity:	149/522 - (28%)
Similarity:	250/522 - (47%)	Gaps:	48/522 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 IILSG--WLL---LAWLYFLWS---RRRYY----KVAWQLRGPIGWPLIGMGLQMMNPETFLQYM 57
            ::|.|  |:|   |||:|..:.   |.|.:    |.:|      .|   |....|.|.|..:|::
  Rat    23 LLLGGASWILARILAWIYTFYDNCCRLRCFPQPPKPSW------FW---GHLTLMKNNEEGMQFI 78

  Fly    58 DGLSRQFKAPFISWMG-TSCFLYINDPHSVEQILNSTHCT--NKGDFYRFMSSAIGDGLFTSSSP 119
            ..|.|.|:...:||:| ....|.:..|:.:..:|.::...  .:...|.|:...:||||..|:..
  Rat    79 AHLGRNFRDIHLSWVGPVYPILRLVHPNVIAPLLQASAAVAPKEMTLYGFLKPWLGDGLLMSAGE 143

  Fly   120 RWHKHRRLINPAFGRQILSNFLPIFNAEAEVLLQKLELEGVQHGKRLEIYQILKKIVLEAACQTT 184
            :|:.||||:.|||...||.:::.|||.....:..|.:....:...||::::.:..:.|::..:..
  Rat   144 KWNHHRRLLTPAFHFDILKSYVKIFNKSVNTMHAKWQRLTAKGSARLDMFEHISLMTLDSLQKCI 208

  Fly   185 MGKKMNFQHDGSLCIFKAYNGLTEVCVKRMLSPWLYPDLIYRRSGLFRLQQKVVGILFGFIEQLL 249
            .....|.|...|..| .|...|:.:.|||...|:||.|.:|..:...|..:|...::..|.:.::
  Rat   209 FSFDSNCQESNSEYI-AAILELSSLIVKRQRQPFLYLDFLYYLTADGRRFRKACDVVHNFTDAVI 272

  Fly   250 EPIVSVVAANSNPDQQRSEMEMRGKSKAI-FIEQV---REHVERGQLSWQDVRDEANVTIAATFE 310
            ....|.:    |.......::.|.|:|.: ||:.:   ::...:| ||..|:|.||:..:....:
  Rat   273 RERRSTL----NTQGVDEFLKARAKTKTLDFIDVLLLAKDEHGKG-LSDVDIRAEADTFMFGGHD 332

  Fly   311 TTSTALYFTILCLAMHPCYQEKLH---KELVTELPPSGDINLEQLQRLEYTEMVINEAMRLFAPV 372
            ||::||.:.:..||.||.|||:..   :||:.:..|. :|..:.|.:|.:..|.|.|::||..||
  Rat   333 TTASALSWILYNLARHPEYQERCRQEVRELLRDREPE-EIEWDDLAQLPFLTMCIKESLRLHPPV 396

  Fly   373 PMVLRSADQDIQLKRGDGEFLIPRGTQIGIDIYNMQRDERVWGPLSRTYNPDAHFGLDSPQ-RHA 436
            .::.|...|||.|.  ||. :||:|....|.|:.:..:..|| |....||| ..|..::|| |..
  Rat   397 LLISRCCSQDIVLP--DGR-VIPKGNICVISIFGVHHNPSVW-PDPEVYNP-FRFDPENPQKRSP 456

  Fly   437 FAFVPFTKGLRMCIGYRYAQMLMKLLLARIFRSYRISTE----ARLEELLVKGNISLKLKDYPLC 497
            .||:||:.|.|.|||..:|...:|:.||.....:.:..:    .|..||:::....|.|:..||.
  Rat   457 LAFIPFSAGPRNCIGQTFAMSEIKVALALTLLRFCVLPDDKEPRRKPELILRAEGGLWLRVEPLS 521

  Fly   498 RV 499
            .|
  Rat   522 TV 523

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313b1	NP_001287239.1	p450	33..474	CDD:299894	129/451 (29%)
Cyp4f6	XP_006241111.1	p450	53..515	CDD:278495	135/482 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920