DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp313b1 and Cyp19a1

DIOPT Version :9

Sequence 1:	NP_001287239.1	Gene:	Cyp313b1 / 41019	FlyBaseID:	FBgn0037601	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_058781.2	Gene:	Cyp19a1 / 25147	RGDID:	2457	Length:	503	Species:	Rattus norvegicus

Alignment Length:	484	Identity:	117/484 - (24%)
Similarity:	202/484 - (41%)	Gaps:	102/484 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 PFIS-----WM--GTSCFLYINDPHSVEQILNSTHCTNK--GDFYRFMSSAIGDGLFTSSSPRWH 122
            |.||     ||  |::|..|                 ||  |:|.|...|.....:.:.||...|
  Rat    58 PLISHGRFLWMGIGSACNYY-----------------NKMYGEFMRVWISGEETLIISKSSSMVH 105

  Fly   123 --KHRRLI-----------------------NPAFGRQILSNFLPIFNAEAEVLLQKLELEGV-Q 161
              ||...|                       ||:..|.:...|:........:.:.::.:|.: |
  Rat   106 VMKHSNYISRFGSKRGLQCIGMHENGIIFNNNPSLWRTVRPFFMKALTGPGLIRMVEVCVESIKQ 170

  Fly   162 HGKRL----------EIYQILKKIVLEAACQTTMGKKMNFQHDGSLCIFKA---YNGLTEVCVKR 213
            |..||          ::..:::.|:|:.:....:|..:    |.|..:.|.   :|....:.:|
  Rat   171 HLDRLGDVTDNSGYVDVVTLMRHIMLDTSNTLFLGIPL----DESSIVKKIQGYFNAWQALLIK- 230

  Fly   214 MLSPWLYPDLIYRRSGLFRLQQKVVGILFGFIEQLLEPIVSVVAANSNPDQQRSEMEMRGKSKAI 278
                   |::.::.|.|:|..::.|..|...||.|:|.....|::     .::.|..|...:..|
  Rat   231 -------PNIFFKISWLYRKYERSVKDLKDEIEILVEKKRQKVSS-----AEKLEDCMDFATDLI 283

  Fly   279 FIEQVREHVERGQLSWQDVRDEANVTIAATFETTSTALYFTILCLAMHPCYQEKLHKELVTELPP 343
            |.|:      ||.|:.::|.......:.|..:|.|..||..:|.:|.:|..:..:.||:.| :..
  Rat   284 FAER------RGDLTKENVNQCILEMLIAAPDTMSVTLYVMLLLIAEYPEVETAILKEIHT-VVG 341

  Fly   344 SGDINLEQLQRLEYTEMVINEAMRLFAPVPMVLRSADQDIQLKRGDGEFLIPRGTQIGIDIYNMQ 408
            ..||.:..:|.|:..|..|||::|....|.:|:|.|.:|..:   || :.:.:||.|.::|..|.
  Rat   342 DRDIRIGDVQNLKVVENFINESLRYQPVVDLVMRRALEDDVI---DG-YPVKKGTNIILNIGRMH 402

  Fly   409 RDERVWGPLSRTYNPDAHFGLDSPQRHAFAFVPFTKGLRMCIGYRYAQMLMKLLLARIFRSYRIS 473
            |.|....|...|..   :|..:.|.|:   |.||..|.|.|.|...|.::||::|..:.:.:.:.
  Rat   403 RLEYFPKPNEFTLE---NFEKNVPYRY---FQPFGFGPRSCAGKYIAMVMMKVVLVTLLKRFHVK 461

  Fly   474 T-EARLEELLVKGN-ISLKL-KDYPLCRV 499
            | :.|..|.:.|.| :||.| :|.|:..:
  Rat   462 TLQKRCIENMPKNNDLSLHLDEDSPIVEI 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313b1	NP_001287239.1	p450	33..474	CDD:299894	107/454 (24%)
Cyp19a1	NP_058781.2	CYP19A1	72..485	CDD:410709	109/463 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010