Protein Alignment Cyp313b1 and Cyp3a9

DIOPT Version :10

• Sequence 1: NP_649807.1
• Gene: Cyp313b1 / 41019
• FlyBaseID: FBgn0037601
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_671739.2
• Gene: Cyp3a9 / 171352
• RGDID: 708392
• Length: 503
• Species: Rattus norvegicus
• Alignment Length: 533
• Identity: 126/533 - (23%)
• Similarity: 221/533 - (41%)
• Gaps: 80/533 - (15%)

  Fly     1 MLASIILSGWLLLA------WLYFLWSRRRYYKVAWQLRGPIGWPLIGMGLQMMNPETFLQYMDG 59
            ::.:..:..||||.      :||...|...:.|:.  :.||...|.:|         |.|.|..|
  Rat     3 LIPNFSMETWLLLVISLVLLYLYGTHSHGIFKKLG--IPGPKPLPFLG---------TILAYRKG 56

  Fly    60 L-------SRQFKAPFISWMGTSCFLYINDPHSVEQILNSTHC----TNKGDF--YRFMSSAIGD 111
            .       .:::...:..:.|....|.|.||..::.:| ...|    ||:.:|  ...:..||.
  Rat    57 FWEFDKYCHKKYGKLWGLYDGRQPVLAITDPDIIKTVL-VKECYSTFTNRRNFGPVGILKKAIS- 119

  Fly   112 GLFTSSSPRWHKHRRLINPAFGRQILSNFLPIFNAEAEVLLQKLELEGVQHGKRLEIYQILKKIV 176
               .|....|.:.|.|::|.|....|....||.|...::|::.:. :|.:.||...:..|.....
  Rat   120 ---ISEDEEWKRIRALLSPTFTSGKLKEMFPIINQYTDMLVRNMR-QGSEEGKPTSMKDIFGAYS 180

  Fly   177 LEAACQTTMG---KKMNFQHD------GSLCIFKAYNGLTEVCVKRMLSPWLYPDL--IYRRSGL 230
            ::....|:.|   ..:|...|      ..|..|..::.|       .||..|:|.|  ::....:
  Rat   181 MDVITATSFGVNVDSLNNPQDPFVEKIKKLLKFDIFDPL-------FLSVTLFPFLTPLFEALNV 238

  Fly   231 FRLQQKVVGILFGFIEQLLEPIVSVVAANSNPDQQRSEMEMRGKSKAIFIEQVREHVERGQLSWQ 295
            ....:.|:......:|::.|        |...::::..|:.    ..:.|......|:....:..
  Rat   239 SMFPRDVIDFFKTSVERMKE--------NRMKEKEKQRMDF----LQLMINSQNSKVKDSHKALS 291

  Fly   296 DVRDEAN--VTIAATFETTSTALYFTILCLAMHPCYQEKLHKELVTELPPSGDINLEQLQRLEYT 358
            ||...|.  :.|.|.:||||:||.|.:..||:||..|:||..|:...||.......:.|.::||.
  Rat   292 DVEIVAQSVIFIFAGYETTSSALSFVLYLLAIHPDIQKKLQDEIDAALPNKAHATYDTLLQMEYL 356

  Fly   359 EMVINEAMRLFAPVPMVLRSADQDIQLKRGDGEFLIPRGTQIGIDIYNMQRDERVWGPLSRTYNP 423
            :||:||.:||:.....:.|....|:::   :|.| ||:||.:.|..:.:.:|...| |....:.|
  Rat   357 DMVVNETLRLYPIAGRLERVCKTDVEI---NGVF-IPKGTVVMIPTFALHKDPHYW-PEPEEFRP 416

  Fly   424 DAHFGLDSPQRHAFAFVPFTKGLRMCIGYRYAQMLMKLLLARIFRSYRISTEARLEELLVKGNIS 488
            :.....:....:.:.::||..|.|.|||.|:|.|.||:.|.|:.:::..       :...:..|.
  Rat   417 ERFSKKNQDNINPYMYLPFGNGPRNCIGMRFALMNMKVALVRVLQNFSF-------QPCKETQIP 474

  Fly   489 LKLKDYPLCRVER 501
            |||....|.:.|:
  Rat   475 LKLSKQGLLQPEK 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313b1	NP_649807.1	CYP313-like	66..498	CDD:410680	109/450 (24%)
Cyp3a9	NP_671739.2	CYP3A	67..492	CDD:410743	110/458 (24%)