Protein Alignment Cyp313b1 and CYP4F22

DIOPT Version :10

• Sequence 1: NP_649807.1
• Gene: Cyp313b1 / 41019
• FlyBaseID: FBgn0037601
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_775754.2
• Gene: CYP4F22 / 126410
• HGNCID: 26820
• Length: 531
• Species: Homo sapiens
• Alignment Length: 516
• Identity: 147/516 - (28%)
• Similarity: 245/516 - (47%)
• Gaps: 45/516 - (8%)

  Fly    11 LLLAWLYFLWSR--------RRYYKVAWQLR-----GPIGWPLIGMGLQMMNPETFLQYMDGLSR 62
            |||..|:||:..        |.:|....:||     ....|.|..:|:.:.| |..||....:..
Human    27 LLLFLLFFLFRLLLRFLRLCRSFYITCRRLRCFPQPPRRNWLLGHLGMYLPN-EAGLQDEKKVLD 90

  Fly    63 QFKAPFISWMGTSC-FLYINDPHSVEQILNSTHCTNKGD--FYRFMSSAIGDGLFTSSSPRWHKH 124
            ......:.|||... .|.:..|..::.:|.::......|  ||.|:...:||||..|...:|.:|
Human    91 NMHHVLLVWMGPVLPLLVLVHPDYIKPLLGASAAIAPKDDLFYGFLKPWLGDGLLLSKGDKWSRH 155

  Fly   125 RRLINPAFGRQILSNFLPIFNAEAEVLLQKLELEGVQHGKRLEIYQILKKIVLEAACQTTMGKKM 189
            |||:.|||...||..::.|||..|:::..|...........|::::.:..:.|::..:.......
Human   156 RRLLTPAFHFDILKPYMKIFNQSADIMHAKWRHLAEGSAVSLDMFEHISLMTLDSLQKCVFSYNS 220

  Fly   190 NFQHDGSLCIFKAYNGLTEVCVKRMLSPWLYPDLIYRRSGLFRLQQKVVGILFGFIEQLLEPIVS 254
            |.|...|..| .|...|:.:.|:|......|.|.||.||...|..::...::..|..::::....
Human   221 NCQEKMSDYI-SAIIELSALSVRRQYRLHHYLDFIYYRSADGRRFRQACDMVHHFTTEVIQERRR 284

  Fly   255 VVAANSNPDQQRSEMEMRGK-SKAI-FIEQV---REHVERG-QLSWQDVRDEANVTIAATFETTS 313
            .:.      ||.:|..::.| .|.: ||:.:   |:  |.| :||.:|:|.||:..:....:|||
Human   285 ALR------QQGAEAWLKAKQGKTLDFIDVLLLARD--EDGKELSDEDIRAEADTFMFEGHDTTS 341

  Fly   314 TALYFTILCLAMHPCYQEKLHKEL--VTELPPSGDINLEQLQRLEYTEMVINEAMRLFAPVPMVL 376
            :.:.:.:..||.:|.||||..:|:  |.:.....::..:.|.:|.:|.|.|.|::|.:.||.:|.
Human   342 SGISWMLFNLAKYPEYQEKCREEIQEVMKGRELEELEWDDLTQLPFTTMCIKESLRQYPPVTLVS 406

  Fly   377 RSADQDIQLKRGDGEFLIPRGTQIGIDIYNMQRDERVWGPLSRTYNPDAHFGLDSP-QRHAFAFV 440
            |...:||:|.  ||. :||:|....:.||....:..|| |.|:.||| ..|..|:| ||...|:|
Human   407 RQCTEDIKLP--DGR-IIPKGIICLVSIYGTHHNPTVW-PDSKVYNP-YRFDPDNPQQRSPLAYV 466

  Fly   441 PFTKGLRMCIGYRYAQMLMKLLLARIFRSYRISTE-----ARLEELLVKGNISLKLKDYPL 496
            ||:.|.|.|||..:|...:::::|.....:|:|.:     .|..||:::....|.||..||
Human   467 PFSAGPRNCIGQSFAMAELRVVVALTLLRFRLSVDRTRKVRRKPELILRTENGLWLKVEPL 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313b1	NP_649807.1	CYP313-like	66..498	CDD:410680	130/448 (29%)
CYP4F22	NP_775754.2	CYP4F	82..523	CDD:410772	128/454 (28%)