Protein Alignment Cyp313b1 and CYP46A1

DIOPT Version :9

• Sequence 1: NP_001287239.1
• Gene: Cyp313b1 / 41019
• FlyBaseID: FBgn0037601
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_006659.1
• Gene: CYP46A1 / 10858
• HGNCID: 2641
• Length: 500
• Species: Homo sapiens
• Alignment Length: 471
• Identity: 121/471 - (25%)
• Similarity: 199/471 - (42%)
• Gaps: 116/471 - (24%)

  Fly    80 INDPHSVEQILNSTHCTNKGDFYRFMSSAIGDGLF------TSSSPRWHKHRRLINPAFGRQILS 138
            :..|.||::.|.||........||.:.:..|:.||      ..:..||||.||:|:.||.|..|.
Human    87 VTSPESVKKFLMSTKYNKDSKMYRALQTVFGERLFGQGLVSECNYERWHKQRRVIDLAFSRSSLV 151

  Fly   139 NFLPIFNAEAEVLLQKLELEGVQHGKRLEIYQILKKIVLEAACQTTMGKKMNFQHDGSLCIFKAY 203
            :.:..||.:||.|::                      :|||                     ||
Human   152 SLMETFNEKAEQLVE----------------------ILEA---------------------KA- 172

  Fly   204 NGLTEVCVKRMLSPWLYPDLIYRRSGLFRLQQKVVGILFGF---IEQLLEPIVSVVAANSN---- 261
            :|.|.|.::.||:   |..:.......|.::   ..:|.|.   :.|.::.::..:.|:.|
Human   173 DGQTPVSMQDMLT---YTAMDILAKAAFGME---TSMLLGAQKPLSQAVKLMLEGITASRNTLAK 231

  Fly   262 --PDQQRSEMEMRGKSKAIFIEQV--------REHVERGQLSWQDV------------RDEANVT 304
              |.:::...|:|...:  |:.||        ||.::||:....|:            .||..:.
Human   232 FLPGKRKQLREVRESIR--FLRQVGRDWVQRRREALKRGEEVPADILTQILKAEEGAQDDEGLLD 294

  Fly   305 IAATF-----ETTSTALYFTILCLAMHPCYQEKLHKELVTELPPSGDINLEQLQRLEYTEMVINE 364
            ...||     ||::..|.||::.|:..|....:|..|:...:.....::.|.|.||:|...|:.|
Human   295 NFVTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIGSKRYLDFEDLGRLQYLSQVLKE 359

  Fly   365 AMRLFAPVPMVLRSADQDIQLKRGDGEFLIPRGTQIGIDIYNMQR-DERVWGPLSRTYNPDAHFG 428
            ::||:.|.....|..:::..:   || ..:|..|.:....|.|.| |.....||  |:||| .||
Human   360 SLRLYPPAWGTFRLLEEETLI---DG-VRVPGNTPLLFSTYVMGRMDTYFEDPL--TFNPD-RFG 417

  Fly   429 LDSPQRHAFAFVPFTKGLRMCIGYRYAQMLMKLLLARIFRSYRISTEARLEELLVKG-------N 486
            ..:| :..|.:.||:.|.|.|||.::|||.:|:::|::.:        |||..||.|       .
Human   418 PGAP-KPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQ--------RLEFRLVPGQRFGLQEQ 473

  Fly   487 ISLKLKDYPLCRVERR 502
            .:||..|..||.:..|
Human   474 ATLKPLDPVLCTLRPR 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313b1	NP_001287239.1	p450	33..474	CDD:299894	109/434 (25%)
CYP46A1	NP_006659.1	p450	34..466	CDD:365848	114/446 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910