Protein Alignment 5-HT2B and Octbeta1R

DIOPT Version :9

• Sequence 1: NP_001262373.1
• Gene: 5-HT2B / 41017
• FlyBaseID: FBgn0261929
• Length: 947
• Species: Drosophila melanogaster
• Sequence 2: NP_001262843.1
• Gene: Octbeta1R / 42652
• FlyBaseID: FBgn0038980
• Length: 508
• Species: Drosophila melanogaster
• Alignment Length: 356
• Identity: 91/356 - (25%)
• Similarity: 156/356 - (43%)
• Gaps: 92/356 - (25%)

  Fly    54 NATGN-ATISATFEDV----------------PFDANNYWALLAL------VLVLGTAAGNILVC 95
            :|.|: ::|:.:.|||                ..|.:::.||:.:      .::|....||:||.
  Fly    65 SAVGSGSSIAVSVEDVVAGQAQDIQASEGSTDDADGSSHLALVFVKCFIIGFIILAAILGNMLVI 129

  Fly    96 LAIAWERRLQNVTNYFLMSLAITDLMVAVLVMPLGILTLVKGYFPLGSEHCLTWICLDVLFCTAS 160
            :::...|:|:.:||||::|||:.|::||:..|......::.|.:..||..|..|...||.|.|||
  Fly   130 VSVMRHRKLRIITNYFVVSLAVADMLVALCAMTFNASVMISGKWMFGSVMCDMWNSFDVYFSTAS 194

  Fly   161 IMHLCTISVDRYLSLRYPMRFGRNKTRRRVTLKIVFVWLLSIAMS-LPL---------SLMYSKN 215
            |||||.||||||.::..|:.:....|:|||.:.::.|||....:| ||:         :..|.|:
  Fly   195 IMHLCCISVDRYYAIVQPLDYPLIMTQRRVFIMLLMVWLSPALLSFLPICSGWYTTTENYKYLKS 259

  Fly   216 HASVLVNGTCQIP-DPVYKLVGSIVCFYIPLGVMLLTYCLTVRLLARQRQNLGGGQQTAAATPGW 279
            :..:     |:.. :..|.:|.|.:.|:|| |:::|:....:...|.:::.|....:.||.
  Fly   260 NPHI-----CEFKVNKAYAIVSSSMSFWIP-GIVMLSMYYRIYQEADRQERLVYRSKVAAL---- 314

  Fly   280 ASGWLGQAPALERRCTWRRLLKPGPGNASSVLHAHSANSTDTDLSTLDNHE-------------- 330
                     .||:.....::.||.|          |.....:.:||:....
  Fly   315 ---------LLEKHLQISQIPKPRP----------SIQVEQSTISTMRRERKAARTLGIIMSAFL 360

  Fly   331 -LWLP-----------DSSIKEPTPTTMTAL 349
             .|||           ||.|   ||..:..:
  Fly   361 ICWLPFFLWYIVSSLCDSCI---TPRLLVGI 388

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
5-HT2B	NP_001262373.1	7tm_1	90..>262	CDD:278431	62/182 (34%)
		7tm_4	90..>238	CDD:304433	55/158 (35%)
Octbeta1R	NP_001262843.1	7tm_4	112..>231	CDD:304433	45/118 (38%)
		7tm_1	124..404	CDD:278431	81/297 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460674
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840