Protein Alignment 5-HT2B and Oct-TyrR

DIOPT Version :9

• Sequence 1: NP_001262373.1
• Gene: 5-HT2B / 41017
• FlyBaseID: FBgn0261929
• Length: 947
• Species: Drosophila melanogaster
• Sequence 2: NP_001163494.1
• Gene: Oct-TyrR / 42452
• FlyBaseID: FBgn0004514
• Length: 601
• Species: Drosophila melanogaster
• Alignment Length: 901
• Identity: 185/901 - (20%)
• Similarity: 296/901 - (32%)
• Gaps: 401/901 - (44%)

  Fly    11 AYNDSGGDDWSSSEHLVLWEEDETQRTTANATSRHNQLHVARWNATGNATISATFEDVPFDANNY 75
            |..||.|:...:.|.|             :|:....||.|..|.|...|.:
  Fly    78 ADKDSAGECEGAVEEL-------------HASILGLQLAVPEWEALLTALV-------------- 115

  Fly    76 WALLALVLVLGTAAGNILVCLAIAWERRLQNVTNYFLMSLAITDLMVAVLVMPLGILTLVKGYFP 140
               |::::|| |..|||||.|::...:.|:.|.|:|::|||:.||.||:||:|..:...:.|.:.
  Fly   116 ---LSVIIVL-TIIGNILVILSVFTYKPLRIVQNFFIVSLAVADLTVALLVLPFNVAYSILGRWE 176

  Fly   141 LGSEHCLTWICLDVLFCTASIMHLCTISVDRYLSLRYPMRFGRNKTRRRVTLKIVFVWLLSIAMS 205
            .|...|..|:..|||.||:||::||.|::|||.::..|:.:.:.:|..||.|.|..|||||:.:|
  Fly   177 FGIHLCKLWLTCDVLCCTSSILNLCAIALDRYWAITDPINYAQKRTVGRVLLLISGVWLLSLLIS 241

  Fly   206 LPLSLMYSKNHASVLVNGT-CQIPDP----VYKLVGSIVCFYIPLGVMLLTYCLTVRLLARQRQN 265
            .| .|:...:......:.| |::...    :|..:||   |:|||.:|.:.| :.:.:..|:|
  Fly   242 SP-PLIGWNDWPDEFTSATPCELTSQRGYVIYSSLGS---FFIPLAIMTIVY-IEIFVATRRR-- 299

  Fly   266 LGGGQQTAAATPGWASGWLGQAPALERRCTWRRL---------LKPGPGNASSVLHAHSANSTDT 321
                                    |..|....:|         |:| ..|:|.|..::|.:.:..
  Fly   300 ------------------------LRERARANKLNTIALKSTELEP-MANSSPVAASNSGSKSRL 339

  Fly   322 DLSTLDNHELWL---PDSSIKEPTPTTMTALHQFGAEMLKLSRGLESVASSSTTGSPTKSEFSLS 383
            ..|       ||   .|.:             ||...|::..:  ||::|.
  Fly   340 LAS-------WLCCGRDRA-------------QFATPMIQNDQ--ESISSE-------------- 368

  Fly   384 NHLQLQYPSSPQRYAATHQQSHHHNHQQHPAGVYHQQASPKGRHGTTVLGLSTTTLGIERESTRN 448
                            |||.               |.:|..|.||
  Fly   369 ----------------THQP---------------QDSSKAGPHG-------------------- 382

  Fly   449 SLASSRMGGEQSDGTLSQLSQRLRAYKKRRRASSAVPGREKRAGHEDADEDVETPTSTLRRHKRH 513
                      .||   .|....:...||.|||
  Fly   383 ----------NSD---PQQQHVVVLVKKSRRA--------------------------------- 401

  Fly   514 NSLPKNALYPRHTTVQESLDDDDDEEEESAQQKDQQTKSKICHSDTELDPPQKAKQCHIAGQNHQ 578
                                               :||..|.|..|.            .|:..|
  Fly   402 -----------------------------------KTKDSIKHGKTR------------GGRKSQ 419

  Fly   579 SDYLQLPSVCTCPYFGDRPLQNCVKSAEVKIISSAFRVTTTTTAVSSSPSEMELLMCSSGNKKSL 643
            |.       .||...|                                  |.:||
  Fly   420 SS-------STCEPHG----------------------------------EQQLL---------- 433

  Fly   644 TSSVSAGITGGPAGAAPATVGSTLSPHSAHNQGSSLTVQSDGSGYLAAPGTPCPGRRKLSISKTA 708
                       |||..    |.:..|...|:.|.    :||.. .....|:...|..::.:::..
  Fly   434 -----------PAGGD----GGSCQPGGGHSGGG----KSDAE-ISTESGSDPKGCIQVCVTQAD 478

  Fly   709 SVVTWDSSRHRRRGSSFGGVRTSLLLTPTKTAT--TSNSSTPLRRSATLRSHQNMNYQGAGECGG 771
            .                   :|||.|||.:::|  .:.|.|||::..:          |..:
  Fly   479 E-------------------QTSLKLTPPQSSTGVAAVSVTPLQKKTS----------GVNQ--- 511

  Fly   772 KTRTTTSSPCMLQRQQTVRSHHSRNSSVISRNSSRHGRIIRLEQKATKVLGVVFFTFVILWSPFF 836
                      .::.:|.:.                    :..|::|.:.||::...|||.|.|||
  Fly   512 ----------FIEEKQKIS--------------------LSKERRAARTLGIIMGVFVICWLPFF 546

  Fly   837 VLNLLPTVCAEC--EERISHWVFDVVTWLGYASSMVNPIFYTIFNKVFRQAFKKVL 890
            ::.::...|..|  ..:..::    :|||||.:|.:||:.|||||..:|:|||::|
  Fly   547 LMYVILPFCQTCCPTNKFKNF----ITWLGYINSGLNPVIYTIFNLDYRRAFKRLL 598

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
5-HT2B	NP_001262373.1	7tm_1	90..>262	CDD:278431	62/176 (35%)
		7tm_4	90..>238	CDD:304433	55/152 (36%)
Oct-TyrR	NP_001163494.1	Zinc_peptidase_like	<113..244	CDD:301362	55/149 (37%)
		7tm_1	126..>293	CDD:278431	62/171 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460649
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840