Protein Alignment 5-HT2B and Dop1R1

DIOPT Version :9

• Sequence 1: NP_001262373.1
• Gene: 5-HT2B / 41017
• FlyBaseID: FBgn0261929
• Length: 947
• Species: Drosophila melanogaster
• Sequence 2: NP_001262563.1
• Gene: Dop1R1 / 41726
• FlyBaseID: FBgn0011582
• Length: 560
• Species: Drosophila melanogaster
• Alignment Length: 351
• Identity: 112/351 - (31%)
• Similarity: 169/351 - (48%)
• Gaps: 69/351 - (19%)

  Fly     8 SLGAYNDSGGDDWSSSEHLVLWEEDETQRTTANA--------------------TSRHNQLHVAR 52
            ::|..:.||...:|::..|:..:....|.|||..                    ||.:|:   :.
  Fly    44 TIGGNHTSGSTGFSTNSTLLDADHLPLQLTTAKVDLDIEIDIQLLTNGYDGTTLTSFYNE---SS 105

  Fly    53 W-NATGNATISATFEDVPFDANNYWALLAL--------VLVLGTAAGNILVCLAIAWERRLQNVT 108
            | ||:...||... |..|.      :|:::        ||:..:.||||||||||..||.|:.:.
  Fly   106 WTNASEMDTIVGE-EPEPL------SLVSIVVVGIFLSVLIFLSVAGNILVCLAIYTERSLRRIG 163

  Fly   109 NYFLMSLAITDLMVAVLVMPLGILTLVKGYFPLGSEHCLTWICLDVLFCTASIMHLCTISVDRYL 173
            |.||.||||.||.||.|||....:..:.||:..|::.|.||:..||:..||||::||.||:|||:
  Fly   164 NLFLASLAIADLFVASLVMTFAGVNDLLGYWIFGAQFCDTWVAFDVMCSTASILNLCAISMDRYI 228

  Fly   174 SLRYPMRFGRNKTRRRVTLKIVFVWLLSIAMS-LPLSLMYSKNHASVLV--NG----TCQIP-DP 230
            .::.|:|:||..|||...:.|..:|||:..:| :|:||...:....::.  ||    ||.:. .|
  Fly   229 HIKDPLRYGRWVTRRVAVITIAAIWLLAAFVSFVPISLGIHRPDQPLIFEDNGKKYPTCALDLTP 293

  Fly   231 VYKLVGSIVCFYIPLGVMLLTYCLTVRLLARQRQNLGGGQQTAAATPGWASGWLGQAPALERRCT 295
            .|.:|.|.:.||.|..||:..||   ||....::::...:  |...|       |:....:|..:
  Fly   294 TYAVVSSCISFYFPCVVMIGIYC---RLYCYAQKHVKSIK--AVTRP-------GEVAEKQRYKS 346

  Fly   296 WRRLLKPGPGNASSV-----LHAHSA 316
            .||     |.|....     ||.||:
  Fly   347 IRR-----PKNQPKKFKVRNLHTHSS 367

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
5-HT2B	NP_001262373.1	7tm_1	90..>262	CDD:278431	77/179 (43%)
		7tm_4	90..>238	CDD:304433	67/155 (43%)
Dop1R1	NP_001262563.1	7tm_4	134..>266	CDD:304433	61/131 (47%)
		7tm_1	145..431	CDD:278431	89/240 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460614
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24247
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940