Protein Alignment 5-HT2B and mAChR-C

DIOPT Version :9

• Sequence 1: NP_001262373.1
• Gene: 5-HT2B / 41017
• FlyBaseID: FBgn0261929
• Length: 947
• Species: Drosophila melanogaster
• Sequence 2: NP_572358.1
• Gene: mAChR-C / 31626
• FlyBaseID: FBgn0029909
• Length: 371
• Species: Drosophila melanogaster
• Alignment Length: 305
• Identity: 82/305 - (26%)
• Similarity: 134/305 - (43%)
• Gaps: 74/305 - (24%)

  Fly    11 AYNDSGGDDW---SSSEHL----VLWEEDETQRTTANATSRHNQLHVARWNATGNATISATFEDV 68
            |:..|....|   ||.|.|    .||:..       |||....::           |:.||
  Fly     2 AFTSSSSPAWDYRSSPEALGVVPFLWQHQ-------NATETPTEI-----------TLQAT---- 44

  Fly    69 PFDANN-YWALL---ALVLVLGTAAGNILVCLAIAWERRLQNV-TNYFLMSLAITDLMVAVLVMP 128
            .|.|.: .|..:   ..||:||   ||||..:|:...|.|::| :|.|::|||::|..|. |.:|
  Fly    45 SFGAGHLLWLAINAFLFVLILG---GNILTIVAVRTCRHLRSVISNLFILSLAVSDFCVG-LALP 105

  Fly   129 LGILTLVKGYFPLGSE------HCLTWICLDVLFCTASIMHLCTISVDRYLSLRYPMRFGRNKTR 187
            ..::      |.:||:      .||....|.:..|..|::.|.:|:||||:::.|.:.:.|..||
  Fly   106 YHLV------FYMGSDIGAMRGPCLLRFFLLICACCVSMLTLISIAVDRYIAVVYALHYRRYMTR 164

  Fly   188 RRVTLKIVFVWLLSIAMSLPLSLMYSKNHASVLVNGTCQIPD---PVYKLVGSIVCFYIPLGV-M 248
            |.....|:|.|.|...::| |.:.:::...:    ..|:..:   |.| :.|.|...::.:.: |
  Fly   165 RVAYSIIIFNWCLGALVAL-LPVFWNRWPDA----QACEFDEVLAPGY-IAGVITPGFVIIWICM 223

  Fly   249 LLTYCLTVRLLARQ----RQNLGGGQQTAAAT--------PGWAS 281
            .|.|...:|..::|    ||::  ...|..||        |.|.|
  Fly   224 FLVYWRIMREASKQALRLRQSV--VYNTDEATTMRNLLLHPDWKS 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
5-HT2B	NP_001262373.1	7tm_1	90..>262	CDD:278431	51/182 (28%)
		7tm_4	90..>238	CDD:304433	46/157 (29%)
mAChR-C	NP_572358.1	7tm_4	61..332	CDD:304433	64/224 (29%)
		7tm_1	67..321	CDD:278431	60/215 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460639
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840