| Sequence 1: | NP_001262373.1 | Gene: | 5-HT2B / 41017 | FlyBaseID: | FBgn0261929 | Length: | 947 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_036900.2 | Gene: | Drd5 / 25195 | RGDID: | 2523 | Length: | 475 | Species: | Rattus norvegicus |
| Alignment Length: | 255 | Identity: | 82/255 - (32%) |
|---|---|---|---|
| Similarity: | 130/255 - (50%) | Gaps: | 39/255 - (15%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 79 LALVLVLGTAAGNILVCLAIAWERRLQ-NVTNYFLMSLAITDLMVAVLVMPLGILTLVKGYFPLG 142
Fly 143 SEHCLTWICLDVLFCTASIMHLCTISVDRYLSLRYPMRFGRNKTRRRVTLKIVFVWLLSIAMS-L 206
Fly 207 PLSLMYSKNHA------SVLVNGT--------------CQIP-DPVYKLVGSIVCFYIPLGVMLL 250
Fly 251 TYCLTVRLLARQRQNLGGGQQTAAATPGWASGWLGQAPALERRCTWRRLLKPGPGNASSV 310 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| 5-HT2B | NP_001262373.1 | 7tmA_5-HT2_insect-like | 74..>267 | CDD:320433 | 75/210 (36%) |
| TM helix 1 | 75..101 | CDD:320433 | 10/21 (48%) | ||
| TM helix 2 | 108..134 | CDD:320433 | 14/25 (56%) | ||
| TM helix 3 | 146..176 | CDD:320433 | 15/29 (52%) | ||
| TM helix 4 | 188..211 | CDD:320433 | 7/23 (30%) | ||
| TM helix 5 | 229..258 | CDD:320433 | 9/28 (32%) | ||
| 7tm_GPCRs | <799..893 | CDD:475119 | |||
| TM helix 6 | 818..840 | CDD:410628 | |||
| TM helix 7 | 854..879 | CDD:410628 | |||
| Drd5 | NP_036900.2 | 7tm_GPCRs | 39..364 | CDD:475119 | 82/255 (32%) |
| TM helix 1 | 41..65 | CDD:410628 | 10/20 (50%) | ||
| TM helix 2 | 75..97 | CDD:410628 | 13/21 (62%) | ||
| TM helix 3 | 112..134 | CDD:410628 | 9/21 (43%) | ||
| TM helix 4 | 157..173 | CDD:410628 | 5/15 (33%) | ||
| TM helix 5 | 217..240 | CDD:410628 | 8/22 (36%) | ||
| TM helix 6 | 289..311 | CDD:410628 | |||
| TM helix 7 | 333..358 | CDD:410628 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 415..443 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||