Protein Alignment pch2 and PCH2

DIOPT Version :9

• Sequence 1: NP_001287235.1
• Gene: pch2 / 41013
• FlyBaseID: FBgn0051453
• Length: 421
• Species: Drosophila melanogaster
• Sequence 2: NP_009745.2
• Gene: PCH2 / 852484
• SGDID: S000000390
• Length: 564
• Species: Saccharomyces cerevisiae
• Alignment Length: 404
• Identity: 138/404 - (34%)
• Similarity: 217/404 - (53%)
• Gaps: 71/404 - (17%)

  Fly    33 ALKAYFQTARKLPRNVSFLPDLTAEQTE-----HVHSV----------LLERD---NGGVQPLKV 79
            ::|..|.....|.:::..:  |.:|:|.     |:.||          |.|:|   ||     .:
Yeast   147 SIKLNFHEKINLGQHIDSI--LDSEETNESDTYHMGSVDEFIIYPFCCLEEQDELKNG-----SI 204

  Fly    80 AETKFRFHFYATRPEEGQLGLFSGEEGSDGIDSI--------------VAASHALLPAAQFVGLW 130
            ..|:|.........::|    |.||..::.|:|:              |..|:  ||...|.|.|
Yeast   205 LSTEFDKIDLELDEDDG----FEGETLNNCINSVGNFDIPLSKQTLNLVNISY--LPGTTFEGQW 263

  Fly   131 ENLIYETGLKEKLLKFALSALMFSEHRVD--------TNVIACNRLILLHGPPGTGKTSLCKALA 187
            |:|.:...:||:|..:|..:|..:..:..        |.:|..|:|:|:|||||||||:|||||.
Yeast   264 ESLYFGNNIKERLYSYATISLKIARFKQTGDSNQEDITTLITNNKLLLVHGPPGTGKTTLCKALC 328

  Fly   188 QKLSIR---TQGSYAYTH-----LVEINSHSLFSKWFSESGKLVAQLFNKIAEL--VSDPNNL-V 241
            ||||:|   :.||.....     ::|::...:|||||.||.|.::.:|..|.||  |::...: :
Yeast   329 QKLSVRREFSDGSDTIDTNYKGIIIELSCARIFSKWFGESSKNISIVFKDIEELLKVNEGRGIFI 393

  Fly   242 CVLIDEVESLAYARSAMSS-NEPRDAMRVVNAVLTQLDSLKTCPNVLILATSNLAQSIDLAFVDR 305
            |:||||||::|.:|:.:|| ||..|.:||||.:|||||.||...|.|.||||||..|:|.|||||
Yeast   394 CLLIDEVEAIASSRTNLSSRNESTDGIRVVNTLLTQLDRLKKYHNFLALATSNLLDSLDDAFVDR 458

  Fly   306 ADIRLFIGYPGISAIREIYKGMLAELMSAGVL----QREVLESEDAEEGLLTQLAER--SVGLSG 364
            ||...::|.|....|..|.|..:.|::::|::    :...::..:..:.:|.::|.:  :|.:||
Yeast   459 ADGVFYVGNPTAEGILHILKVCIEEMITSGIILFHARSTGVKFFNKYQDILRKIAIKCSTVDISG 523

  Fly   365 RTLRKLPLLAHAQY 378
            ||:|||||:..::|
Yeast   524 RTIRKLPLMCLSEY 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pch2	NP_001287235.1	AAA	166..315	CDD:214640	81/160 (51%)
		AAA	169..314	CDD:278434	78/156 (50%)
PCH2	NP_009745.2	SpoVK	1..487	CDD:223540	124/352 (35%)
		P-loop_NTPase	248..465	CDD:422963	96/218 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	135	1.000	Domainoid score	I1087
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H3125
Inparanoid	1	1.050	185	1.000	Inparanoid score	I937
Isobase	1	0.950	-	0	Normalized mean entropy	S1847
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005740
OrthoInspector	1	1.000	-	-		oto98950
orthoMCL	1	0.900	-	-		OOG6_103946
Panther	1	1.100	-	-	LDO	PTHR45991
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2222
SonicParanoid	1	1.000	-	-		X4134
TreeFam	1	0.960	-	-
	13	12.800