Protein Alignment pch2 and CDC48

DIOPT Version :9

• Sequence 1: NP_001287235.1
• Gene: pch2 / 41013
• FlyBaseID: FBgn0051453
• Length: 421
• Species: Drosophila melanogaster
• Sequence 2: NP_010157.1
• Gene: CDC48 / 851431
• SGDID: S000002284
• Length: 835
• Species: Saccharomyces cerevisiae
• Alignment Length: 456
• Identity: 106/456 - (23%)
• Similarity: 181/456 - (39%)
• Gaps: 128/456 - (28%)

  Fly    18 GNDLRSNAI-------RNNVETALKAYFQTARKLPRNVSFLPDLTAE-QTEHVHSVLLE-RDNGG 73
            |...|||.:       .|:::.||:.:.:..|::...:   ||.|.. :...:|:..:: .|:..
Yeast   344 GMKARSNVVVIAATNRPNSIDPALRRFGRFDREVDIGI---PDATGRLEVLRIHTKNMKLADDVD 405

  Fly    74 VQPLKVAETKFRFHFY------------ATRPEEGQLGLFSGEEGSDGIDSIVAASHALL----- 121
            ::.| .|||    |.|            |.:....::.|...:|  |.||:.|..|..:.
Yeast   406 LEAL-AAET----HGYVGADIASLCSEAAMQQIREKMDLIDLDE--DEIDAEVLDSLGVTMDNFR 463

  Fly   122 -------PAA------QFVGL-WENLIYETGLKEKL--------------LKFALSALMFSEHRV 158
                   |:|      :.|.: |:::.....:||:|              .||.||.
Yeast   464 FALGNSNPSALRETVVESVNVTWDDVGGLDEIKEELKETVEYPVLHPDQYTKFGLSP-------- 520

  Fly   159 DTNVIACNRLILLHGPPGTGKTSLCKALAQKLSIRTQGSYAYTHLVEINSHSLFSKWFSESGKLV 223
                   ::.:|.:||||||||.|.||:|.::|         .:.:.:....|.|.|:.||...:
Yeast   521 -------SKGVLFYGPPGTGKTLLAKAVATEVS---------ANFISVKGPELLSMWYGESESNI 569

  Fly   224 AQLFNKIAELVSDPNNLVCVLIDEVESLAYARSAMSSNEPRDAMRVVNAVLTQLDSLKTCPNVLI 288
            ..:|:|......     ..|.:||::|:|.||.....:....:.||||.:||::|.:....||.:
Yeast   570 RDIFDKARAAAP-----TVVFLDELDSIAKARGGSLGDAGGASDRVVNQLLTEMDGMNAKKNVFV 629

  Fly   289 LATSNLAQSIDLAFV--DRADIRLFIGYPGISAIREIYKGMLAELMSAGVLQREVLESEDAEEGL 351
            :..:|....||.|.:  .|.|..:::..|..:|...|....              |.....|.||
Yeast   630 IGATNRPDQIDPAILRPGRLDQLIYVPLPDENARLSILNAQ--------------LRKTPLEPGL 680

  Fly   352 -LTQLAERSVGLSGRTLRKLPLLAHAQYTSSTLFELDQKISLSDFLDAMLEALEQHLGEQRLLKL 415
             ||.:|:.:.|.||..|  |.::..|           .|.::.|    .:||..||..|:. :|:
Yeast   681 ELTAIAKATQGFSGADL--LYIVQRA-----------AKYAIKD----SIEAHRQHEAEKE-VKV 727

  Fly   416 E 416
            |
Yeast   728 E 728

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pch2	NP_001287235.1	AAA	166..315	CDD:214640	43/150 (29%)
		AAA	169..314	CDD:278434	43/146 (29%)
CDC48	NP_010157.1	CDC48	48..785	CDD:273521	106/456 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810