Protein Alignment pch2 and AFG2

DIOPT Version :10

• Sequence 1: NP_524282.4
• Gene: pch2 / 41013
• FlyBaseID: FBgn0051453
• Length: 421
• Species: Drosophila melanogaster
• Sequence 2: NP_013501.1
• Gene: AFG2 / 851113
• SGDID: S000004389
• Length: 780
• Species: Saccharomyces cerevisiae
• Alignment Length: 429
• Identity: 103/429 - (24%)
• Similarity: 169/429 - (39%)
• Gaps: 108/429 - (25%)

  Fly    60 EHVHSVLLERDNGGVQPLKVAETKFRFHFYATRPEEGQLGLFSGEEGSDGI------DSIVAASH 118
            |.|...||: |:|.:.|..:      |....|:         :|:|..|.:      ||:...|.
Yeast   145 EKVIQKLLD-DSGVIMPGMI------FQNLKTK---------AGDESIDVVITDASDDSLPDVSQ 193

  Fly   119 ALLPAAQFVGLWENLIY------------------ET------------------GLKEKL--LK 145
            ..|......|..:||.|                  ||                  ||.:::  ||
Yeast   194 LDLNMDDMYGGLDNLFYLSPPFIFRKGSTHITFSKETQANRKYNLPEPLSYAAVGGLDKEIESLK 258

  Fly   146 FALSALMFSEHRVDTNVIACNRLILLHGPPGTGKTSLCKALAQKLSIRTQGSYAYTHLVEINSHS 210
            .|:...:.......:..::..|.||||||||||||.|.:.:|         :.:..|::.||..|
Yeast   259 SAIEIPLHQPTLFSSFGVSPPRGILLHGPPGTGKTMLLRVVA---------NTSNAHVLTINGPS 314

  Fly   211 LFSKWFSESGKLVAQLFNKIAELVSDPNNLVCVLIDEVESLAYARSAMSSNEPRDAMRVVNAVLT 275
            :.||:..|:...:..:||:..:.  .|:   .:.|||::|:|..|:...|.|...  |||..:||
Yeast   315 IVSKYLGETEAALRDIFNEARKY--QPS---IIFIDEIDSIAPNRANDDSGEVES--RVVATLLT 372

  Fly   276 QLDSLKTCPNVLILATSNLAQSIDLAF--VDRADIRLFIGYPGISAIREIYKGMLAELMSAGVLQ 338
            .:|.:.....|:::|.:|...|:|.|.  ..|.|..:.||.|.:.|..:|.....:.:.|    .
Yeast   373 LMDGMGAAGKVVVIAATNRPNSVDPALRRPGRFDQEVEIGIPDVDARFDILTKQFSRMSS----D 433

  Fly   339 REVLESEDAEEGLLTQLAERSVGLSGRTLRKL------PLLAHAQYTSSTLFELDQKISLSDFLD 397
            |.||:||     .:..:|.::.|..|..|..|      ..:.....|.:.:.:...|::|.|...
Yeast   434 RHVLDSE-----AIKYIASKTHGYVGADLTALCRESVMKTIQRGLGTDANIDKFSLKVTLKDVES 493

  Fly   398 AMLEA---------LE------QHLGEQRLLKLESMEQL 421
            ||::.         ||      ..:|.|..||.:..|.:
Yeast   494 AMVDIRPSAMREIFLEMPKVYWSDIGGQEELKTKMKEMI 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pch2	NP_524282.4	RecA-like_Pch2-like	115..312	CDD:410916	60/236 (25%)
AFG2	NP_013501.1	CDC48	51..773	CDD:273521	103/429 (24%)