DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pch2 and spata5l1

DIOPT Version :9

Sequence 1:	NP_001287235.1	Gene:	pch2 / 41013	FlyBaseID:	FBgn0051453	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	NP_001070056.2	Gene:	spata5l1 / 767648	ZFINID:	ZDB-GENE-060929-204	Length:	748	Species:	Danio rerio

Alignment Length:	361	Identity:	93/361 - (25%)
Similarity:	150/361 - (41%)	Gaps:	75/361 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 LPDLTAEQTEHVHSVLLERDNGGVQPLKVAETKFRFHFYATRPEEGQLGLFSGEEGSDGIDSIVA 115
            |.||:..:.| :..||:|:.|.|.|                     :.||.:.....| |.:|..
Zfish   132 LVDLSGVKAE-IRCVLVEKVNSGSQ---------------------RAGLITARTCVD-ISTIQT 173

  Fly   116 ASH-----ALLPAAQFVGLWENLIYETGLKEKL---LKFALSALMFSEHRVDTNVIACNRLILLH 172
            ..|     ..:.||...|: |::.  ..|||.:   |::..|.....        ::|.|.:||.
Zfish   174 VKHLDRQQQQVSAAPLGGM-EDVF--ASLKEMITFPLRYPGSLRQLG--------LSCPRGLLLI 227

  Fly   173 GPPGTGKTSLCKALAQKLSIRTQGSYAYTHLVEINSHSLFSKWFSESGKLVAQLFNKIAELVSD- 236
            ||||.|||.|.:.:|:.:.         ..||.:|...:......||.:.:.::|.:..:...|
Zfish   228 GPPGVGKTLLVRCVAKDIG---------ATLVTVNGPEVTGSRPGESEENLRRVFEQARDAADDG 283

  Fly   237 PNNLVCV-LIDEVESLAYARSAMSSNEPRDAMRVVNAVLTQLDSLKTCPNVLILATSNLAQSIDL 300
            |    || ||||::||...|:. ||:.|.:  |:|..:||.:|::.:....:|:..:|...|:|.
Zfish   284 P----CVLLIDEIDSLCPRRTG-SSSAPEN--RLVAQLLTLMDAIGSHEGFVIIGATNQPDSLDP 341

  Fly   301 AF--VDRADIRLFIGYPGISAIREIYKGMLAELMSAGVLQREVLESEDAEEGLLTQLAERSVGLS 363
            |.  ..|.|..:.||.|.:...|.|.|          .:.||:..|.|.:   |..|||.:.|..
Zfish   342 ALRRPGRFDREVIIGVPSLLQRRSILK----------CVCREMPLSPDVD---LNTLAEMTCGYV 393

  Fly   364 GRTLRKLPLLAHAQYTSSTLFELDQKISLSDFLDAM 399
            |..|..|...|..|....:.....:.:|:..|:.|:
Zfish   394 GADLSALSREAALQAMRHSQMGASEPVSMQHFMQAL 429

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pch2	NP_001287235.1	AAA	166..315	CDD:214640	46/152 (30%)
pch2	NP_001287235.1	AAA	169..314	CDD:278434	44/148 (30%)
spata5l1	NP_001070056.2	CDC48	13..740	CDD:273521	93/361 (26%)
		AAA	224..357	CDD:278434	44/148 (30%)
		AAA	489..655	CDD:278434
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900