DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pch2 and Spata5

DIOPT Version :9

Sequence 1:	NP_001287235.1	Gene:	pch2 / 41013	FlyBaseID:	FBgn0051453	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	NP_001156983.1	Gene:	Spata5 / 57815	MGIID:	1927170	Length:	893	Species:	Mus musculus

Alignment Length:	247	Identity:	68/247 - (27%)
Similarity:	114/247 - (46%)	Gaps:	34/247 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   163 IACNRLILLHGPPGTGKTSLCKALAQKLSIRTQGSYAYTHLVEINSHSLFSKWFSESGKLVAQLF 227
            |...|.:||:||||||||.:.:|:|.::     |:|...    ||...:.||::.|:...:.|:|
Mouse   384 IPAPRGLLLYGPPGTGKTMIARAVANEV-----GAYVSV----INGPEIISKFYGETEARLRQIF 439

  Fly   228 NKIAELVSDPNNLVCVLIDEVESLAYARSAMSSNEPRDAMRVVNAVLTQLDSLKTCPN---VLIL 289
            .:..  :..|:   .:.|||:::|...|....|...:   |||.::||.:|.:.:..:   ||:|
Mouse   440 AEAT--LRHPS---IIFIDELDALCPKREGAQSEVEK---RVVASLLTLMDGIGSEGSEGRVLVL 496

  Fly   290 ATSNLAQSIDLAF--VDRADIRLFIGYPGISAIREIYKGMLAELMSAGVLQREVLESEDAEEG-- 350
            ..:|..|::|.|.  ..|.|..:.||.|......:|.:.:|..:... :.:.|:|...:...|
Mouse   497 GATNRPQALDAALRRPGRFDKEIEIGIPNAQDRLDILQKLLRRVPHL-LTKAELLRLANNAHGYV 560

  Fly   351 ---LLTQLAERSVGLSGRTLRKLPLLAHAQYTSSTLFELDQKISLSDFLDAM 399
               |.....|..:....|.|||.|.|..::.....      ||:|:|||..|
Mouse   561 GADLKALCNEAGLHALRRVLRKQPNLPDSKVAGMV------KITLNDFLQGM 606

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pch2	NP_001287235.1	AAA	166..315	CDD:214640	46/153 (30%)
pch2	NP_001287235.1	AAA	169..314	CDD:278434	44/149 (30%)
Spata5	NP_001156983.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..38
		CDC48_N	64..132	CDD:304500
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	202..227
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	239..315
		SpoVK	370..882	CDD:223540	68/247 (28%)
		AAA	390..522	CDD:278434	43/148 (29%)
		AAA	664..796	CDD:278434
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900