Protein Alignment pch2 and PEX1

DIOPT Version :10

• Sequence 1: NP_524282.4
• Gene: pch2 / 41013
• FlyBaseID: FBgn0051453
• Length: 421
• Species: Drosophila melanogaster
• Sequence 2: NP_000457.1
• Gene: PEX1 / 5189
• HGNCID: 8850
• Length: 1283
• Species: Homo sapiens
• Alignment Length: 272
• Identity: 76/272 - (27%)
• Similarity: 116/272 - (42%)
• Gaps: 50/272 - (18%)

  Fly   169 ILLHGPPGTGKTSLCKALAQKLSIRTQGSYAYTHLVEINSHSLFSKWFSESGKLVAQLFNKIAEL 233
            |||:||||||||.|...:|::         :..:.:.:....|.||:...|.:.|..:|  |...
Human   877 ILLYGPPGTGKTLLAGVIARE---------SRMNFISVKGPELLSKYIGASEQAVRDIF--IRAQ 930

  Fly   234 VSDPNNLVCVL-IDEVESLAYARSAMSSNEPRDAMRVVNAVLTQLDSLKTCPNVLILATSNLAQS 297
            .:.|    |:| .||.||:| .|....:....|  ||||.:|||||.::....|.:||.::....
Human   931 AAKP----CILFFDEFESIA-PRRGHDNTGVTD--RVVNQLLTQLDGVEGLQGVYVLAATSRPDL 988

  Fly   298 IDLAFV--DRADIRLFIGYPGISAIREIYKGMLAELMSAGVLQREVLESEDAEEGLLTQLAERSV 360
            ||.|.:  .|.|..::...|          ..::.|....||...:..::|.:   |..:|..:.
Human   989 IDPALLRPGRLDKCVYCPPP----------DQVSRLEILNVLSDSLPLADDVD---LQHVASVTD 1040

  Fly   361 GLSGRTLRKLPLLA-----HAQYTSSTLFE----LDQKISLSD--FLDAML----EALEQHLG-E 409
            ..:|..|:.|...|     |....||.|.:    .|..:|||.  ||:...    .|.:...| :
Human  1041 SFTGADLKALLYNAQLEALHGMLLSSGLQDGSSSSDSDLSLSSMVFLNHSSGSDDSAGDGECGLD 1105

  Fly   410 QRLLKLESMEQL 421
            |.|:.||..|.|
Human  1106 QSLVSLEMSEIL 1117

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pch2	NP_524282.4	RecA-like_Pch2-like	115..312	CDD:410916	47/145 (32%)
PEX1	NP_000457.1	PEX-2N	17..98	CDD:462730
		PEX-1N	104..179	CDD:462729
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	346..367
		CDC48	<595..1065	CDD:273521	59/218 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1260..1283