DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pch2 and nvl

DIOPT Version :9

Sequence 1:	NP_001287235.1	Gene:	pch2 / 41013	FlyBaseID:	FBgn0051453	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	NP_998649.1	Gene:	nvl / 406805	ZFINID:	ZDB-GENE-040426-2871	Length:	796	Species:	Danio rerio

Alignment Length:	187	Identity:	53/187 - (28%)
Similarity:	87/187 - (46%)	Gaps:	25/187 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   169 ILLHGPPGTGKTSLCKALAQKLSIRTQGSYAYTHLVEINSHSLFSKWFSESGKLVAQLFNKIAEL 233
            :||.||||.|||.|.||:|....:         :.:.:....|.:.:..||.:.|.|:|.:
Zfish   557 LLLAGPPGCGKTLLAKAVANASGL---------NFISVKGPELLNMYVGESERAVRQVFQR---- 608

  Fly   234 VSDPNNLVCVL-IDEVESLAYARSAMSSNEPRDAMRVVNAVLTQLDSLKTCPNVLILATSNLAQS 297
              ..|:..||: .||:::|...|   |.:|...::||||.:||::|.::....|.|:|.:|....
Zfish   609 --GRNSAPCVIFFDEIDALCPRR---SEHESGASVRVVNQLLTEMDGMENRRQVFIMAATNRPDI 668

  Fly   298 IDLAFV--DRADIRLFIGYPGI----SAIREIYKGMLAELMSAGVLQREVLESEDAE 348
            ||.|.:  .|.|..|::|.|..    :.:..|.||.....:.:.|...|:......|
Zfish   669 IDPAVLRPGRLDKTLYVGLPPAADRHAILNTITKGGTKPQLDSDVSLEEIAHDARCE 725

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pch2	NP_001287235.1	AAA	166..315	CDD:214640	46/148 (31%)
pch2	NP_001287235.1	AAA	169..314	CDD:278434	45/147 (31%)
nvl	NP_998649.1	Nucleolin_bd	2..71	CDD:293330
		RNA_polI_A34	<165..215	CDD:285426
		SpoVK	246..792	CDD:223540	53/187 (28%)
		AAA	264..395	CDD:278434
		P-loop_NTPase	537..>573	CDD:304359	10/15 (67%)
		AAA	557..687	CDD:278434	45/147 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.900