DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pch2 and CG12010

DIOPT Version :9

Sequence 1:	NP_001287235.1	Gene:	pch2 / 41013	FlyBaseID:	FBgn0051453	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	NP_728878.1	Gene:	CG12010 / 38421	FlyBaseID:	FBgn0035443	Length:	717	Species:	Drosophila melanogaster

Alignment Length:	240	Identity:	56/240 - (23%)
Similarity:	105/240 - (43%)	Gaps:	49/240 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   169 ILLHGPPGTGKTSLCKALAQKLSIRTQGSYAYTHLVEINSHSLFSKWFSESGKLVAQLFNKIAEL 233
            :||:||||..||::.|.||::..:    ::..|...|:     :|.:...:.:.::::|:...:
  Fly   487 VLLYGPPGCAKTTVAKCLAKEADM----TFIATSAAEV-----YSPYVGCAERFISRIFDTARK- 541

  Fly   234 VSDPNNLVC-VLIDEVESLAYARSAMSSNEPRDA-MRVVNAVLTQLDSL---KTCPNVLILATSN 293
                 |..| :.:||::||...|:..|....... :|:::.:||:::.:   .:..::|::|.:|
  Fly   542 -----NAPCLIFLDEIDSLVGRRTVSSGGGGGQVQLRILSTLLTEMNGIVGGGSQQHILVVAATN 601

  Fly   294 LAQSIDLAFV--DRADIRLFIGYPGISAIREIYKGMLAELMSAGVLQREVLESEDA---EEGLLT 353
            ....||.|.:  .|.|..:.:..|.       .|..||.|.         |.|:..   |...|.
  Fly   602 RPDMIDDALLRPGRFDKLIHVPAPD-------EKSRLALLK---------LHSQRMPFHENVFLQ 650

  Fly   354 QLAERSVGLSGRTLRKLPLLAHAQYTSSTLFELDQK---ISLSDF 395
            ::|.|:...||..|..|     ....:...|:.|.|   |.|.||
  Fly   651 EIAARTDRYSGADLCNL-----CNEAAIEAFQRDFKATEIELQDF 690

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pch2	NP_001287235.1	AAA	166..315	CDD:214640	34/152 (22%)
pch2	NP_001287235.1	AAA	169..314	CDD:278434	34/151 (23%)
CG12010	NP_728878.1	SpoVK	201..707	CDD:223540	56/240 (23%)
		AAA	224..357	CDD:278434
		AAA	487..623	CDD:278434	34/150 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900