DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pch2 and nsfa

DIOPT Version :9

Sequence 1:	NP_001287235.1	Gene:	pch2 / 41013	FlyBaseID:	FBgn0051453	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	XP_021325418.1	Gene:	nsfa / 368483	ZFINID:	ZDB-GENE-030616-37	Length:	747	Species:	Danio rerio

Alignment Length:	289	Identity:	66/289 - (22%)
Similarity:	131/289 - (45%)	Gaps:	48/289 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   143 LLKFALSALMFSEHRVDTNVIACNRL--ILLHGPPGTGKTSLCKALAQKLSIRTQGSYAYTHLVE 205
            :.:.|.::.:|....|:.  :.|..:  |||.||||.|||.:.:.:.:.|:.|....
Zfish   230 IFRRAFASRVFPPDIVEQ--MGCKHVKGILLFGPPGCGKTLMARQIGKMLNAREPKI-------- 284

  Fly   206 INSHSLFSKWFSESGKLVAQLFNKIAE---LVSDPNNLVCVLIDEVESLAYAR-SAMSSNEPRDA 266
            :|...:.:|:..||...:.:||....|   .:...:.|..::.||::::...| :..||....|.
Zfish   285 VNGPEILNKYVGESEANIRKLFADAEEEQKRLGANSGLHIIIFDELDAICKQRGTGASSTGVHDT 349

  Fly   267 MRVVNAVLTQLDSLKTCPNVLILATSNLAQSIDLAFV--DRADIRLFIGYP---GISAIREIYKG 326
              |||.:|:::|.::...|:|::..:|....||.|.:  .|.::::.||.|   |...|..|:..
Zfish   350 --VVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALMRPGRFEVKMEIGLPDEKGRVQILNIHTA 412

  Fly   327 MLAELMSAGVLQREVLESE-DAEEGLLTQLAERSVGLSGRTLRKLPLLA-------HAQYTSSTL 383
            .:.|.        ::|.|: |.:|     ||..:...||..|..|...|       |.:.||:..
Zfish   413 KMREF--------KLLASDVDVKE-----LAAETKNYSGAELEGLVRAAQSTAMNRHIKATSTVE 464

  Fly   384 FELDQ----KISLSDFLDAMLEALEQHLG 408
            .::::    :::.:||:.::...::...|
Zfish   465 VDMERAEKLQVTRTDFMASLNNDIKPAFG 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pch2	NP_001287235.1	AAA	166..315	CDD:214640	40/156 (26%)
pch2	NP_001287235.1	AAA	169..314	CDD:278434	39/150 (26%)
nsfa	XP_021325418.1	CDC48_N	6..83	CDD:215012
		CDC48_2	111..183	CDD:215011
		TIP49	160..>606	CDD:332389	66/289 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900