Protein Alignment pch2 and Katnal2

DIOPT Version :10

• Sequence 1: NP_524282.4
• Gene: pch2 / 41013
• FlyBaseID: FBgn0051453
• Length: 421
• Species: Drosophila melanogaster
• Sequence 2: NP_001419361.1
• Gene: Katnal2 / 307253
• RGDID: 1564708
• Length: 537
• Species: Rattus norvegicus
• Alignment Length: 486
• Identity: 117/486 - (24%)
• Similarity: 193/486 - (39%)
• Gaps: 116/486 - (23%)

  Fly     7 SDTVHVEVCLRGNDLRSNAIRNNVETALKAYFQTARKLPRNVSFLPDLTAEQTEH-----VHSVL 66
            ||.|...:..|..........:|.:...|.|.|.:|  |:..:.....|....||     |.:..
  Rat    94 SDQVENNISSRSGGKNKRLTNDNCQNLPKIYHQKSR--PKTSTVKTGDTKSVKEHPKQESVTNAQ 156

  Fly    67 LERDNGGVQPLKV----AETKFRFHFYATRPEEGQLGLFSG--EEGSDGIDSIVA---------- 115
            .|..:.|:...|:    .|.|       ..|..||:..|.|  .:...|..|..|
  Rat   157 AESSDFGLNISKIHKDSPEEK-------AHPRRGQIIDFRGLLTDAIKGATSEYALNTFECNPDP 214

  Fly   116 ASHALLPAAQFVGL-----------------------WENLIYETGLKEKLLKFALSALMFSEHR 157
            :...|.|.:.|:|:                       |.::|.....|:.:.:..:..:.:.:
  Rat   215 SERLLKPLSAFIGMNSEMRELAAVVSRDIYLHNPNIKWNDIIGLDAAKQLVKEAVVYPIRYPQ-- 277

  Fly   158 VDTNVIACNRLILLHGPPGTGKTSLCKALAQKLSIRTQGSYAYTHLVEINSHSLFSKWFSESGKL 222
            :.|.:::..:.:||:||||||||.|.||:|.:..         |....|::.::.|||..:|.||
  Rat   278 LFTGILSPWKGLLLYGPPGTGKTLLAKAVATECK---------TTFFNISASTIVSKWRGDSEKL 333

  Fly   223 VAQLFNKIAELV--SDPNNLVCVLIDEVESLAYARSAMSSNEPRDAMRVVNAVLTQLDSLKTCPN 285
            |..||    ||.  ..|:.   :.:||:||:...|..:...|...::|:...:|.|:|.|....:
  Rat   334 VRVLF----ELARYHAPST---IFLDELESVMSQRGMVPGGEHEGSLRMKTELLVQMDGLARSED 391

  Fly   286 -VLILATSNLAQSIDLAFVDRADIRLFIGYPGISAIREIYKGMLAELMSAGVLQREVLESEDAEE 349
             |.:||.|||...:|.|.:.|.:.|:.:..|.    :|..:.|:...:.. |.:...||
  Rat   392 LVFVLAASNLPWELDCAMLRRLEKRILVDLPS----QEARQAMIYHWLPP-VSKNHALE------ 445

  Fly   350 GLLTQ-----LAERSVGLSG------------RTLRKL-PLLAHAQYTSSTL--FELDQKISLSD 394
             |.||     |::.:.|.||            |.:||: .:|.:.|..||.|  .:|| .::..|
  Rat   446 -LRTQLEYSVLSQETEGYSGSDIKLVCREAAMRPVRKIFNVLENHQSESSNLLGIQLD-TVTTED 508

  Fly   395 FLDAMLEA-------LEQHLGEQRLLKLESM 418
            |||.:...       .|::|..|.  |.||:
  Rat   509 FLDVLAHTKPSAKNLTERYLAWQE--KFESV 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pch2	NP_524282.4	RecA-like_Pch2-like	115..312	CDD:410916	58/232 (25%)
Katnal2	NP_001419361.1	LisH	25..55	CDD:128913
		RPT1	184..525	CDD:440835	90/371 (24%)
		RecA-like_VPS4-like	255..419	CDD:410917	52/181 (29%)