DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pch2 and nsf-1

DIOPT Version :9

Sequence 1:	NP_001287235.1	Gene:	pch2 / 41013	FlyBaseID:	FBgn0051453	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	NP_001076603.1	Gene:	nsf-1 / 266842	WormBaseID:	WBGene00003818	Length:	824	Species:	Caenorhabditis elegans

Alignment Length:	407	Identity:	91/407 - (22%)
Similarity:	158/407 - (38%)	Gaps:	97/407 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 ARKLPRNVSFLPDLTAEQTEHVHSVLLERD-----NGGVQPLK--VAETKFRFHFYATRPEEGQL 98
            |..|.:.|...| .|.:|:|:|.|::|..|     |...:||.  :...:|...|......:|..
Worm   135 ALSLDQEVRVTP-FTFQQSEYVGSMILTADFNAKKNVTSEPLNADLMAREFSIQFGGQAFSKGMQ 198

  Fly    99 GLFSGE-----------------EGSDGIDSIVAASHA-----------------LLPAAQFV-- 127
            ..|..|                 ||.|...:..|||.|                 |||.:..|
Worm   199 MAFRFEDKEKNKTHTLSLVVKSIEGFDIGKAAAAASGASNTDSSATKPKQIEAGELLPNSVIVFD 263

  Fly   128 ---GLWENLIYET----------------------GLKEK---LLKFALSALMFSEHRVDTNVIA 164
               |...|||.::                      ||..:   :.:.|.::.:|....::...:.
Worm   264 KEEGSMLNLIGKSKGKSAYRSIINPDWDFQQMGIGGLDTEFSHIFRRAFASRVFPPEFIEQLGMK 328

  Fly   165 CNRLILLHGPPGTGKTSLCKALAQKLSIRTQGSYAYTHLVEINSHSLFSKWFSESGKLVAQLFNK 229
            ..|.|||.||||||||.:.:.:.:.|:.|....        :|...:..|:..||...|.:||..
Worm   329 HVRGILLFGPPGTGKTLMARQIGKMLNAREPKI--------VNGPQILDKYVGESESNVRKLFAD 385

  Fly   230 IAE---LVSDPNNLVCVLIDEVESLAYARSAMS-SNEPRDAMRVVNAVLTQLDSLKTCPNVLILA 290
            ..|   .....:.|..::.||::::...|.:|: |:...|.  |||.:|:::|.::...|:|::.
Worm   386 AEEEWRRCGANSGLHIIIFDEIDAICKQRGSMAGSSSVHDT--VVNQLLSKMDGVEQLNNILVIG 448

  Fly   291 TSNLAQSIDLAFV--DRADIRLFIGYPGISAIREIYKGMLAELMSAGVLQREVLESEDAEEGLLT 353
            .:|....||.|.:  .|.::::.:..|..:...:|.|...|.:.....:...|    |.|:
Worm   449 MTNRRDMIDEALLRPGRLEVQMEVSLPDETGRLQILKIHTARMREYNKMDPNV----DLED---- 505

  Fly   354 QLAERSVGLSGRTLRKL 370
             :::|:...||..|..|
Worm   506 -ISKRTKNFSGAELEGL 521

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pch2	NP_001287235.1	AAA	166..315	CDD:214640	41/154 (27%)
pch2	NP_001287235.1	AAA	169..314	CDD:278434	40/150 (27%)
nsf-1	NP_001076603.1	CDC48_N	68..147	CDD:215012	4/12 (33%)
		CDC48_2	174..>222	CDD:215011	7/47 (15%)
		AAA	331..476	CDD:214640	41/154 (27%)
		AAA	333..474	CDD:278434	40/150 (27%)
		AAA	609..746	CDD:99707
		AAA	614..748	CDD:214640
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910