DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pch2 and figl-1

DIOPT Version :9

Sequence 1:	NP_001287235.1	Gene:	pch2 / 41013	FlyBaseID:	FBgn0051453	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	NP_504197.1	Gene:	figl-1 / 178829	WormBaseID:	WBGene00017981	Length:	594	Species:	Caenorhabditis elegans

Alignment Length:	403	Identity:	100/403 - (24%)
Similarity:	160/403 - (39%)	Gaps:	98/403 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 EVCLRGNDLRSN--------------AIRNNVETALKAYFQTARKLPRNVSF------------- 50
            |..|:|.::.||              ||:|.:.|...::...|.:.|:|..|
Worm   177 ENTLKGIEVASNPHFKKTRAPTKNRAAIQNTLGTLYPSFTTAAGQDPQNSKFQVPLDRQSSSQSI 241

  Fly    51 -----------LPDLTAEQTEHVHSVLLERD-NGGVQPLKV----AETKFRFHFYATRPEEGQLG 99
                       .||:....:..:....:..| .||.:..|:    ||...: ||     :|..:.
Worm   242 GSLAGIPPARRAPDIPKRCSNPLIRKAMGMDTEGGGKDEKMSGLRAEPTLK-HF-----DENIIS 300

  Fly   100 LFSGEEGSDGIDSIVAASHALLPAAQFVGLWENLIYETGLKEKLLKFALSALMFSEHRVDTNVIA 164
            |...|               ::.....:| |.::....|.|:.|.:..:  |.|....|.|.:.|
Worm   301 LIESE---------------IMSVNNEIG-WADVAGLEGAKKALREIVV--LPFKRPDVFTGIRA 347

  Fly   165 CNRLILLHGPPGTGKTSLCKALAQKLSIRTQGSYAYTHLVEINSHSLFSKWFSESGKLVAQLFNK 229
            ..:.:||.||||||||.:.:.:|         |........|::.||.|||..|..|||..||:
Worm   348 PPKGVLLFGPPGTGKTMIGRCVA---------SQCKATFFNISASSLTSKWVGEGEKLVRALFS- 402

  Fly   230 IAELVSDPNNLVCVLIDEVESLAYARSAMSSNEPRDAMRVVNAVLTQLDSLKTCPN--VLILATS 292
            :|.| ..|:   .:.|||::||.   |:.|.:|...:.|:....|.|||.:.|.|:  :|:|..:
Worm   403 VARL-KLPS---VIFIDEIDSLL---SSRSESEHESSRRIKTEFLVQLDGVNTAPDERLLVLGAT 460

  Fly   293 NLAQSIDLAFVDRADIRLFIGYPGISAIREIYKGMLAELMSAGVLQREVLESEDAEEGLLTQLAE 357
            |..|.:|.|...|...||:|..|...:..:|.:.:|            |....|.....|.::.|
Worm   461 NRPQELDEAARRRFQKRLYIALPEPESRTQIVQNLL------------VGTRHDITNHNLERIRE 513

  Fly   358 RSVGLSGRTLRKL 370
            .:.|.||..:|:|
Worm   514 LTDGYSGADMRQL 526

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pch2	NP_001287235.1	AAA	166..315	CDD:214640	52/150 (35%)
pch2	NP_001287235.1	AAA	169..314	CDD:278434	52/146 (36%)
figl-1	NP_504197.1	P-loop_NTPase	315..>371	CDD:304359	20/66 (30%)
		AAA	348..484	CDD:214640	52/152 (34%)
		AAA	352..480	CDD:278434	51/144 (35%)
		Vps4_C	<545..585	CDD:286426
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900