DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pch2 and cdc-48.1

DIOPT Version :9

Sequence 1:	NP_001287235.1	Gene:	pch2 / 41013	FlyBaseID:	FBgn0051453	Length:	421	Species:	Drosophila melanogaster
Sequence 2:	NP_496273.1	Gene:	cdc-48.1 / 174624	WormBaseID:	WBGene00007352	Length:	809	Species:	Caenorhabditis elegans

Alignment Length:	246	Identity:	73/246 - (29%)
Similarity:	109/246 - (44%)	Gaps:	47/246 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   129 LWENLIYETGLKEKLLKFALSALMFSEHRVDTNVIACNRLILLHGPPGTGKTSLCKALAQKLSIR 193
            |.|.:.|.....||.|||.:..               :|.:|.:||||.|||.|.||:|.:
Worm   495 LQELVQYPVEHPEKYLKFGMQP---------------SRGVLFYGPPGCGKTLLAKAIANE---- 540

  Fly   194 TQGSYAYTHLVEINSHSLFSKWFSESGKLVAQLFNKIAELVSDPNNLVCVL-IDEVESLAYARSA 257
                 ...:.:.|....|.:.||.||...|..:|:|......      ||| .||::|:|.||..
Worm   541 -----CQANFISIKGPELLTMWFGESEANVRDVFDKARAAAP------CVLFFDELDSIAKARGG 594

  Fly   258 MSSNEPRDAM-RVVNAVLTQLDSLKTCPNVLILATSNLAQSIDLAFV--DRADIRLFIGYPGISA 319
            .:..:...|. ||:|.|||::|.:....||.|:..:|....||.|.:  .|.|..::|..|..::
Worm   595 GAGGDGGGASDRVINQVLTEMDGMNAKKNVFIIGATNRPDIIDPAVLRPGRLDQLIYIPLPDEAS 659

  Fly   320 IREIYKGMLAELMSAGVLQREVLESEDAEEGLLTQLAERSVGLSGRTLRKL 370
            ..:|.|..|          |:...|:|.:   ||.||:.:||.||..|.::
Worm   660 RHQILKASL----------RKTPLSKDLD---LTFLAKNTVGFSGADLTEI 697

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pch2	NP_001287235.1	AAA	166..315	CDD:214640	49/152 (32%)
pch2	NP_001287235.1	AAA	169..314	CDD:278434	48/148 (32%)
cdc-48.1	NP_496273.1	CDC48_N	31..112	CDD:280513
		CDC48	52..775	CDD:273521	73/246 (30%)
		CDC48_2	137..197	CDD:215011
		AAA	247..376	CDD:278434
		AAA	520..654	CDD:278434	48/148 (32%)
		Vps4_C	<727..771	CDD:286426
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810