Protein Alignment pch2 and pch-2

DIOPT Version :9

• Sequence 1: NP_001287235.1
• Gene: pch2 / 41013
• FlyBaseID: FBgn0051453
• Length: 421
• Species: Drosophila melanogaster
• Sequence 2: NP_495711.1
• Gene: pch-2 / 174313
• WormBaseID: WBGene00008641
• Length: 424
• Species: Caenorhabditis elegans
• Alignment Length: 447
• Identity: 164/447 - (36%)
• Similarity: 238/447 - (53%)
• Gaps: 71/447 - (15%)

  Fly     1 MSFLSNSDTVHVEVCLRGNDLRSNAIR--NNVETALKAYFQTAR--------KLPRNVSFLPDL- 54
            |..|.|   :|.|:.:.....:|...:  :..|..:||..:.||        :|.:..|.|.:|
 Worm     5 MKTLKN---IHAEIRICQKFPKSTVQKRFSEFEELIKAASKNARNWKPISSVELFQGDSSLNELF 66

  Fly    55 -----------TAEQTEHVHSVLLERDNGGVQPLKVAETKFRFHFYATRPEEGQLGLFSGEEGSD 108
                       ..|..|:|:.:.:...|              .|.|... ::|.|....|::  |
 Worm    67 EKLVIGTCELRDGELFENVNDLTINPSN--------------IHVYKLH-KDGPLSQNIGDD--D 114

  Fly   109 GIDSIVAASHALLPAAQFVGLWENLIYETGLKEKLLKFALSALMFSEHRVDTNVIACNRLILLHG 173
            |.:||:.:....||..:|..:||||||::.||.:::.:..:....||..|:|.:|..||||||.|
 Worm   115 GDESIIGSQLWQLPCVEFDSIWENLIYDSNLKNEVMSYVAALARLSEKHVNTKIINVNRLILLTG 179

  Fly   174 PPGTGKTSLCKALAQKLSIRTQGSYAYTHLVEINSHSLFSKWFSESGKLVAQLFNKIAELVSDPN 238
            |||||||||||.|||.||||....|:.:.::|||||||||||||||||||.::|::|.||..|..
 Worm   180 PPGTGKTSLCKGLAQHLSIRMNDKYSKSVMLEINSHSLFSKWFSESGKLVQKMFDQIDELAEDEK 244

  Fly   239 NLVCVLIDEVESLAYARSAMSS-NEPRDAMRVVNAVLTQLDSLKTCPNVLILATSNLAQSIDLAF 302
            .:|.|||||||||...|.:.|| :||.||:|.|||:|||:|.::...|||||.||||..::|.|.
 Worm   245 CMVFVLIDEVESLGMCRESSSSRSEPSDAIRAVNALLTQIDRIRRRDNVLILCTSNLESTLDKAL 309

  Fly   303 VDRADIRLFIGYPGISAIREIYKGMLAELMSAGVLQREVLESE-----------DAE------EG 350
            ||||||...:|.|...|...:.|..:.||...||    |:::|           |.:      ..
 Worm   310 VDRADIVKNVGQPSDFARYSMLKSSIMELARIGV----VIDNEVHTDYWPQDICDTKAPRNEFTE 370

  Fly   351 LLTQLAERSVGLSGRTLRKLPLLAHAQYTSSTLFELDQKISLSDFLDAMLEALEQHL 407
            :|.::|:.:.|||||.:..||.|.:::....|       |:|.:.::..|||:::.|
 Worm   371 ILFKIAQEARGLSGRAISMLPTLVYSKSPEET-------ITLPNCMNLFLEAVKERL 420

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pch2	NP_001287235.1	AAA	166..315	CDD:214640	93/149 (62%)
		AAA	169..314	CDD:278434	89/145 (61%)
pch-2	NP_495711.1	AAA	172..322	CDD:214640	93/149 (62%)
		AAA	175..320	CDD:278434	89/144 (62%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	167	1.000	Domainoid score	I2340
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	238	1.000	Inparanoid score	I2128
Isobase	1	0.950	-	0	Normalized mean entropy	S1847
OMA	1	1.010	-	-		QHG57461
OrthoDB	1	1.010	-	-		D1036414at2759
OrthoFinder	1	1.000	-	-		FOG0005740
OrthoInspector	1	1.000	-	-		oto17391
orthoMCL	1	0.900	-	-		OOG6_103946
Panther	1	1.100	-	-	LDO	PTHR45991
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2222
SonicParanoid	1	1.000	-	-		X4134
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.820