Protein Alignment pch2 and Vcp

DIOPT Version :10

• Sequence 1: NP_524282.4
• Gene: pch2 / 41013
• FlyBaseID: FBgn0051453
• Length: 421
• Species: Drosophila melanogaster
• Sequence 2: NP_446316.1
• Gene: Vcp / 116643
• RGDID: 621595
• Length: 806
• Species: Rattus norvegicus
• Alignment Length: 245
• Identity: 67/245 - (27%)
• Similarity: 108/245 - (44%)
• Gaps: 46/245 - (18%)

  Fly   129 LWENLIYETGLKEKLLKFALSALMFSEHRVDTNVIACNRLILLHGPPGTGKTSLCKALAQKLSIR 193
            |.|.:.|.....:|.|||.::.               ::.:|.:||||.|||.|.||:|.:
  Rat   489 LQELVQYPVEHPDKFLKFGMTP---------------SKGVLFYGPPGCGKTLLAKAIANE---- 534

  Fly   194 TQGSYAYTHLVEINSHSLFSKWFSESGKLVAQLFNKIAELVSDPNNLVCVL-IDEVESLAYARSA 257
                 ...:.:.|....|.:.||.||...|.::|:|..:...      ||| .||::|:|.||..
  Rat   535 -----CQANFISIKGPELLTMWFGESEANVREIFDKARQAAP------CVLFFDELDSIAKARGG 588

  Fly   258 MSSNEPRDAMRVVNAVLTQLDSLKTCPNVLILATSNLAQSIDLAFV--DRADIRLFIGYPGISAI 320
            ...:....|.||:|.:||::|.:.|..||.|:..:|....||.|.:  .|.|..::|..|.
  Rat   589 NIGDGGGAADRVINQILTEMDGMSTKKNVFIIGATNRPDIIDPAILRPGRLDQLIYIPLPD---- 649

  Fly   321 REIYKGMLAELMSAGVLQREVLESEDAEEGLLTQLAERSVGLSGRTLRKL 370
                     |.....:|:..:.:|..|::..|..||:.:.|.||..|.::
  Rat   650 ---------EKSRVAILKANLRKSPVAKDVDLEFLAKMTNGFSGADLTEI 690

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pch2	NP_524282.4	RecA-like_Pch2-like	115..312	CDD:410916	54/185 (29%)
Vcp	NP_446316.1	CDC48	25..764	CDD:273521	67/245 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	708..727
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	768..806
		Interaction with UBXN6. /evidence=ECO:0000250	797..806
		PIM motif. /evidence=ECO:0000250|UniProtKB:P55072	802..806