Protein Alignment CG31259 and Tmem135

DIOPT Version :10

• Sequence 1: NP_731251.1
• Gene: CG31259 / 41010
• FlyBaseID: FBgn0051259
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: XP_030098876.1
• Gene: Tmem135 / 72759
• MGIID: 1920009
• Length: 543
• Species: Mus musculus
• Alignment Length: 433
• Identity: 138/433 - (31%)
• Similarity: 216/433 - (49%)
• Gaps: 72/433 - (16%)

  Fly    47 ATVYVFALIMRGRIPSLK-DLRRTASGILQSTAFLSMNGGLFVFAVCYLRQILGGFYFGTVAWLP 110
            |.::..|.::|.|  .|: .|.:....||||.:||:.||.|::...|.||:|||.||    :|.|
Mouse   128 ALLFQIAAVLRKR--KLEYYLYKLLPEILQSASFLTANGALYITFFCILRKILGKFY----SWTP 186

  Fly   111 SF----LASFACLAFERPERRAPLALYVANVGIETLWKMMEARGWVRSIPNGQVFIMGASVTALM 171
            .|    .||:..:..||..||..|.:|:||:..|||::|..|||.:.::.||:|.:.  .:||.|
Mouse   187 GFGAALPASYVAILIERKSRRGLLTIYMANLATETLFRMGVARGTITTLRNGEVLLF--CITAAM 249

  Fly   172 YLY----RAGLHKTVAKDPTFKAIALIVGKEDEGPLKTPVVTTTQSSRQAPLNFQ---------- 222
            |::    :.||     |..||.|:..|||||:       :.|.:.|...|....:
Mouse   250 YMFFFRCKDGL-----KGFTFSALRFIVGKEE-------IPTHSYSPETAYAKVEQKREKHKGTP 302

  Fly   223 ---SISAYVQ-LYDRMLK--AKHPSCPH-KRGCVPYALIGGLKPFLGGVGLSVG--LKLLLNIPK 278
               ||.|.|: |.|.:.|  .:|..|.| :..|:.|.:.|.::.|      |||  ::..|.||.
Mouse   303 RAMSIIALVRTLVDSVCKHGPRHRCCKHYEDNCISYCIKGFIRMF------SVGYLIQCCLRIPS 361

  Fly   279 IFKSKMQWRKHIF-----------NGGSLQLGLALGIFSFLFKSTTCGLRHTFGFDNALFAIPAG 332
            .|       :|:|           |..:.|||..||.|..::|.|:|.||.....|:.|.||.||
Mouse   362 AF-------RHLFTEPSRLLSLFYNKENFQLGAFLGSFVSIYKGTSCFLRWIRNLDDELHAIVAG 419

  Fly   333 LIGSIGFFRFPNTTVACYLMWKSMHLLYNWGIAEGKLPEVPHFAMLMYGFFTAVLFHSAILEARS 397
            .:..:....:.:||::.||..|.:..:|..||..||:|..|....::|...||:.||:|::|.::
Mouse   420 FLAGVSMMFYKSTTISMYLASKLVETMYFKGIEAGKVPYFPQADTIIYSISTAICFHAAVMEVQN 484

  Fly   398 LRPSYYKFLMGISGNRISRFNVKPFEAYGLKSQDQINYVIKKL 440
            |||||:|||:.::..|.:..|.|..:.:|..:..:.:..|.:|
Mouse   485 LRPSYWKFLLRLTKGRFALMNRKALDVFGTGASREFHNFIPRL 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31259	NP_731251.1	TMEM135_C_rich	16..145	CDD:374269	39/102 (38%)
Tmem135	XP_030098876.1	TMEM135_C_rich	<130..227	CDD:374269	39/102 (38%)
		Tim17	<384..436	CDD:460567	19/51 (37%)