Protein Alignment CG11737 and Tmem135

DIOPT Version :10

• Sequence 1: NP_649803.1
• Gene: CG11737 / 41009
• FlyBaseID: FBgn0037592
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: XP_030098876.1
• Gene: Tmem135 / 72759
• MGIID: 1920009
• Length: 543
• Species: Mus musculus
• Alignment Length: 466
• Identity: 143/466 - (30%)
• Similarity: 227/466 - (48%)
• Gaps: 72/466 - (15%)

  Fly    21 PWTDHCVSATAG----ILLSATPYCLRVYTIVYALSLLMRHRIPSRDDLRKTLLGIIQSTAFLVT 81
            |...||.....|    .||.:.|      .:::.::.::|.| .....|.|.|..|:||.:||..
Mouse   105 PTRIHCTLWPGGDGAPWLLPSQP------ALLFQIAAVLRKR-KLEYYLYKLLPEILQSASFLTA 162

  Fly    82 NAYTFILYNCALRHMLGRYNFYTVAFVPCFLASFSAILVERPARRPLLTLYVANVATEALWKMAE 146
            |...:|.:.|.||.:||::..:|..|.....||:.|||:||.:||.|||:|:||:|||.|::|..
Mouse   163 NGALYITFFCILRKILGKFYSWTPGFGAALPASYVAILIERKSRRGLLTIYMANLATETLFRMGV 227

  Fly   147 SRGWVRSVPNGQTLIFGVSMAALLYIYRTGTTKDSI----FNILRIFVGKEEAGPIVKSGPAVPG 207
            :||.:.::.||:.|:|.::.|..::.:|   .||.:    |:.||..|||||.
Mouse   228 ARGTITTLRNGEVLLFCITAAMYMFFFR---CKDGLKGFTFSALRFIVGKEEI------------ 277

  Fly   208 EQPAPDRRRPTVSFSTVSDWVRVYSN---------------LIRA----------KHESCRH-QQ 246
                     ||.|:|..:.:.:|...               |:|.          :|..|:| :.
Mouse   278 ---------PTHSYSPETAYAKVEQKREKHKGTPRAMSIIALVRTLVDSVCKHGPRHRCCKHYED 333

  Fly   247 SCIGYSLMGGIKPFVGGVGLQVALKLVMNVKRITAGKMPWKKMIFNRGTLQLGIFMGSFSFLYKS 311
            :||.|.:.|.|:.|..|..:|..|::....:.:.........:.:|:...|||.|:|||..:||.
Mouse   334 NCISYCIKGFIRMFSVGYLIQCCLRIPSAFRHLFTEPSRLLSLFYNKENFQLGAFLGSFVSIYKG 398

  Fly   312 VSCLLRHSFNRDDARFAIPASLIASISFTQYPDNTVALYVMWKALQILCTKGQEHGIVPHIPNFM 376
            .||.||...|.||...||.|..:|.:|...|...|:::|:..|.::.:..||.|.|.||:.|...
Mouse   399 TSCFLRWIRNLDDELHAIVAGFLAGVSMMFYKSTTISMYLASKLVETMYFKGIEAGKVPYFPQAD 463

  Fly   377 LFLYSFFTAVLFHAGILEPKSLRPSYYKFLQAISGDRLSKFNLSAFDVFGLSSQQQALDTIKALN 441
            ..:||..||:.|||.::|.::|||||:|||..::..|.:..|..|.||||..:.::..:.|..|:
Mouse   464 TIIYSISTAICFHAAVMEVQNLRPSYWKFLLRLTKGRFALMNRKALDVFGTGASREFHNFIPRLD 528

  Fly   442 IVEKSSLPAYS 452
                   |.|:
Mouse   529 -------PRYT 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11737	NP_649803.1	TMEM135_C_rich	15..145	CDD:374269	45/127 (35%)
Tmem135	XP_030098876.1	TMEM135_C_rich	<130..227	CDD:374269	39/97 (40%)
		Tim17	<384..436	CDD:460567	23/51 (45%)