Protein Alignment CG11737 and tmem-135

DIOPT Version :10

• Sequence 1: NP_649803.1
• Gene: CG11737 / 41009
• FlyBaseID: FBgn0037592
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_508800.2
• Gene: tmem-135 / 180740
• WormBaseID: WBGene00019345
• Length: 445
• Species: Caenorhabditis elegans
• Alignment Length: 446
• Identity: 114/446 - (25%)
• Similarity: 203/446 - (45%)
• Gaps: 43/446 - (9%)

  Fly     1 MAGQSKLIDP-----LCITCKEFQHPWTDHCVSATAGILLSATPYCLRVYTIVYALSLLM--RHR 58
            |...|||...     |..||.|..|.|...|..|....|.....:.|:.|...|.::.::  |.|
 Worm     1 MGALSKLAHSLGQPILTATCYETIHTWNPDCNGAFFDALPVGLIFSLKTYASFYLITNVVSKRGR 65

  Fly    59 IPSRDDLRKTLLGIIQSTAFLVTNAYTFILYNCALRHMLGRYNFYTVAFVPCFLASFSAILVERP 123
            : .:.:.:|..:.:.||:.|||||...|::..|..|..||.:...|:..|...|||..|||||:.
 Worm    66 L-DKINWKKFGIDVCQSSLFLVTNMCFFLILLCKFRKWLGFFTPITMGLVSSILASGIAILVEKK 129

  Fly   124 ARRPLLTLYVANVATEALWKMAESRGWVRSVPNGQTLIFGVSMAALLYIYRTGTTKDSIFNILRI 188
            :|||.|.||:.|:|:|..::...:.|:|.....|:.:.||:.:....::...|....|....:.:
 Worm   130 SRRPALALYLINLASETYYRHLANHGYVTMHTYGECIPFGIGLMLFTWLQSIGRLPKSFNGFMNV 194

  Fly   189 FVGKEEAGPIVKSGPAVPGEQPAPDRRRPTVSFSTVSDWVRVYSNLIRA---KHESCRHQQSCIG 250
            .:....:..::       .|:..||.             .|::...:|:   |.|.|.|..||:.
 Worm   195 ALKSNVSENLI-------NEKKIPDN-------------FRLFLEKLRSDYKKTELCNHPHSCVS 239

  Fly   251 YSLMGGIKPFVGGVGLQVALKLVMNVKRITAGKMPWKKMIFNRGTLQLGIFMGSFSFLYKSVSCL 315
            :|:....|....|:.....|.::.||:.|....:....::.::..|:|.:|.|...|::.:..|
 Worm   240 HSVESFAKNMTFGLTASSVLTVIRNVRTIIKNPLNLITLLVSKENLKLPLFAGFLPFIFNATRC- 303

  Fly   316 LRHSFNRDDARFAIP------ASLIASISFTQYPDNTVALYVMWKALQILCTKGQEHGIVPHIPN 374
               |.||  .::..|      ::.:||::...||..::|:|.:|||::.:.....:.|.:|...|
 Worm   304 ---SLNR--VKYVPPVLNNVFSAGLASVAMAFYPTVSIAMYCLWKAIETVYFDLVDRGYLPKFKN 363

  Fly   375 FMLFLYSFFTAVLFHAGILEPKSLRPSYYKFLQAISGDRLSKFNLSAFDVFGLSSQ 430
            ..:.||:..|..:....::||:::|..|..||..:.|.::|.||...:|.||..|:
 Worm   364 GEVILYAITTGYVLWNAVVEPRAIRRGYLNFLFGLVGGKISLFNRRLYDHFGFVSR 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11737	NP_649803.1	TMEM135_C_rich	15..145	CDD:374269	44/131 (34%)
tmem-135	NP_508800.2	TMEM135_C_rich	20..149	CDD:374269	44/129 (34%)