DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Or85b and Or49a

DIOPT Version :9

Sequence 1:	NP_524279.2	Gene:	Or85b / 41007	FlyBaseID:	FBgn0037590	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_523711.3	Gene:	Or49a / 36350	FlyBaseID:	FBgn0033727	Length:	396	Species:	Drosophila melanogaster

Alignment Length:	428	Identity:	98/428 - (22%)
Similarity:	191/428 - (44%)	Gaps:	80/428 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MEKLMKYASFFYTA------VG---------------IRPY------TNGEESKMNKLIFHIVFW 38
            ||||..|..|.:.|      :|               :|.|      :|..|:.|  :...|:.|
  Fly     1 MEKLRSYEDFIFMANMMFKTLGYDLFHTPKPWWRYLLVRGYFVLCTISNFYEASM--VTTRIIEW 63

  Fly    39 SNVINLSFVGLFESIYVYSAFMDNKFLEAVTALSYIGFVTVGMSKMFFIRWKKTAITELINELKE 103
            .::.......:.:.::.:....           |.:.|:|      |.|..|:  :.:|.:.|||
  Fly    64 ESLAGSPSKIMRQGLHFFYMLS-----------SQLKFIT------FMINRKR--LLQLSHRLKE 109

  Fly   104 IYPNGLIREERYNLPMYLGTCSRISLIYSLLYSVLIWTFNLF---CVMEY-------WVYDKWLN 158
            :||:....:.:|.:..|..:||..:::|...:.:::......   |:|..       :.|.:...
  Fly   110 LYPHKEQNQRKYEVNKYYLSCSTRNVLYVYYFVMVVMALEPLVQSCIMYLIGFGKADFTYKRIFP 174

  Fly   159 IRVV---GKQLPY-LMYIPWKWQDNWSYYPLLFSQNFAGYTSAAGQISTDVLLCAVATQLVMHFD 219
            .|:.   .|.|.| |.|:          ....:||.....:     :.||:.:..|::|:.||..
  Fly   175 TRLTFDSEKPLGYVLAYV----------IDFTYSQFIVNVS-----LGTDLWMMCVSSQISMHLG 224

  Fly   220 FLSNSMERHELSGDW-KKDSRFLVDIVRYHERILRLSDAVNDIFGIPLLLNFMVSSFVICFVGFQ 283
            :|:|.:.....|.:. ::|..||..|::.|:.::||...||.:||:.|..|...:|.::|.:.:.
  Fly   225 YLANMLASIRPSPETEQQDCDFLASIIKRHQLMIRLQKDVNYVFGLLLASNLFTTSCLLCCMAYY 289

  Fly   284 MTV-GVPPDIVVKLFLFLVSSMSQVYLICHYGQLVADASYGFSVATYNQKWYKADVRYKRALVII 347
            ..| |...:.:..:.|| .|..:|.|::..:||::.|.|...:.|.:..|||:..:|||:.::|:
  Fly   290 TVVEGFNWEGISYMMLF-ASVAAQFYVVSSHGQMLIDLSTNLAKAAFESKWYEGSLRYKKEILIL 353

  Fly   348 IARSQKVTFLKATIFLDITRSTMTDLLQISYKFFALLR 385
            :|::|:...:.|...:.|:..|...|:.|:|:|||::|
  Fly   354 MAQAQRPLEISARGVIIISLDTFKILMTITYRFFAVIR 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Or85b	NP_524279.2	7tm_6	64..378	CDD:251636	78/329 (24%)
Or49a	NP_523711.3	7tm_6	88..384	CDD:251636	77/319 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45472786
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2EMAZ
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D407395at33208
OrthoFinder	1	1.000	-	-		FOG0005297
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR21137
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850