DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7963 and CG4854

DIOPT Version :9

Sequence 1:	NP_649798.3	Gene:	CG7963 / 41001	FlyBaseID:	FBgn0037584	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	NP_650860.1	Gene:	CG4854 / 42391	FlyBaseID:	FBgn0038766	Length:	319	Species:	Drosophila melanogaster

Alignment Length:	337	Identity:	85/337 - (25%)
Similarity:	140/337 - (41%)	Gaps:	50/337 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 SGEFRCRVCLKQ--DELLVDIYEIVEEMQVDLCTLLETCGGIKVDRRDVQPMYLCQECTNELLIA 67
            |.:.:||:||.|  ||.|:       ..:.|....::.|.|:::......|..:|..|...|..|
  Fly     7 SRDLKCRICLVQPKDESLM-------PTEPDFPDKIKRCTGVELSESPDWPNRICTSCALLLRAA 64

  Fly    68 AKFRKICVESEK-LRDM-APEINIDTAEPLASEEIIIIDPSDYIEQLSAVEDPENEPIGVSRWNC 130
            .|.|.:|.::|| |::. ..||||:          |:.|..:..::..:.:..:||..|..
  Fly    65 LKLRSLCQQTEKDLKEQKLQEINIE----------IVHDEQETKKKTESRDLSKNEATGSD---- 115

  Fly   131 QHCGAGFQLSEVLRRHIQEVHASITI---IDCRERRRIFTKLGCYQVHNCSYAKTPK-------- 184
                     ||:...::.....::..   :.|.....:..:..........|:.:||
  Fly   116 ---------SELEYEYLDSYDVTLESSEDVACSADELVSIEPAISAPEESVYSLSPKPVTFEDED 171

  Fly   185 ----RGHKCLECGKCLQSASSLASHIRLHTDEWPFTCDQCAKAFRTNGALEVHQRRHKQVLQHKC 245
                ....|..|.........|.:|:::|:.:.|..|:.|.|.||....|..|...|.....:||
  Fly   172 SGQAASFTCNICNNVYSERVKLTNHMKVHSAKKPHECEICHKRFRQTPQLARHMNTHTGNRPYKC 236

  Fly   246 LHCGRGFVESSNLRRHIVNRHTEERPHLCNVYQRSFSRVYMLELHLRTNTGERPYACQHRDKRFA 310
            .:|...|.:.|...:| ...||.|||:.|....|||....:|.:||:|:|||||::||:..|.|:
  Fly   237 DYCDSRFADPSTRIKH-QRIHTNERPYKCEFCSRSFGYSNVLRVHLKTHTGERPFSCQYCQKSFS 300

  Fly   311 QLGVLKIHERIH 322
            ||.....||:.|
  Fly   301 QLHHKNSHEKSH 312

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7963	NP_649798.3	zf-AD	10..80	CDD:285071	21/72 (29%)
		C2H2 Zn finger	159..179	CDD:275368	1/19 (5%)
		COG5048	184..>250	CDD:227381	18/77 (23%)
		C2H2 Zn finger	189..209	CDD:275368	4/19 (21%)
		C2H2 Zn finger	217..237	CDD:275368	7/19 (37%)
		C2H2 Zn finger	245..262	CDD:275368	4/16 (25%)
		C2H2 Zn finger	274..294	CDD:275368	7/19 (37%)
		C2H2 Zn finger	302..322	CDD:275368	8/19 (42%)
		zf-H2C2_2	315..339	CDD:290200	3/8 (38%)
		C2H2 Zn finger	330..350	CDD:275368
CG4854	NP_650860.1	zf-AD	12..>57	CDD:285071	13/51 (25%)
		C2H2 Zn finger	180..200	CDD:275368	4/19 (21%)
		zf-H2C2_2	193..217	CDD:290200	8/23 (35%)
		COG5048	201..>258	CDD:227381	16/57 (28%)
		C2H2 Zn finger	208..228	CDD:275368	7/19 (37%)
		zf-H2C2_2	221..244	CDD:290200	6/22 (27%)
		C2H2 Zn finger	236..256	CDD:275368	5/20 (25%)
		zf-H2C2_2	251..273	CDD:290200	10/22 (45%)
		C2H2 Zn finger	264..284	CDD:275368	7/19 (37%)
		zf-H2C2_2	277..301	CDD:290200	13/23 (57%)
		C2H2 Zn finger	292..312	CDD:275368	8/19 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	0	0.000