DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7963 and CG4424

DIOPT Version :9

Sequence 1:	NP_649798.3	Gene:	CG7963 / 41001	FlyBaseID:	FBgn0037584	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	NP_650859.3	Gene:	CG4424 / 42390	FlyBaseID:	FBgn0038765	Length:	345	Species:	Drosophila melanogaster

Alignment Length:	372	Identity:	102/372 - (27%)
Similarity:	155/372 - (41%)	Gaps:	100/372 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 CRVCLKQDEL-LVDIYEIVEEM---QVDLCTLLETCGGIKV---DRRDVQPMYLCQECTNELLIA 67
            ||.||:..|. :|.|::..::.   .|.||..:|:..||::   .:.:|.|..:|..|...|.:|
  Fly    11 CRTCLQDGEAHMVSIFQTADDRLPGGVSLCDKIESLSGIQIRATAKEEVLPTRICLRCKAFLTLA 75

  Fly    68 AKFRKIC---------------VESEKLRDMAPEINIDTAEPLASEEIIIIDPSDYIEQLSAVED 117
            .|||:||               ||...::::..:....|..|:.:|::               |.
  Fly    76 HKFRQICQRSNEFLREYVIKDAVEQGVVKEVVQQTRPSTPPPIETEQL---------------EP 125

  Fly   118 PENEPIGVSRWNCQHCGAGFQLSEVLRRHIQEV-HASITIIDCRERRRIFTKLGCYQVHNCSY-- 179
            ||:|.:....|:.:.             .|:|. |....    :||..:.|    .::....|
  Fly   126 PEDEVLEEGVWSTED-------------PIEETPHGPAE----KERPTVLT----VEMLPAPYPP 169

  Fly   180 -AKTPK-------RG--HKCLECGKCLQSASSLASHIRLHTDEWPFTCDQCAKAFRTNGALEVHQ 234
             |.||.       :|  |.|..||......|:|.:|:|.|.||.|:.|:.|.|:|..|
  Fly   170 PASTPPPAPAGAVKGKLHVCAICGNGYPRKSTLDTHMRRHNDERPYECEICHKSFHVN------- 227

  Fly   235 RRHKQVLQHKCLHCGRGFVESSNLRRHIVNRHTEERPHLCNVYQRSFSRVYMLELHLRTNTGERP 299
                                 ..|:||| .:||..:|:.|...||:|:....|..|.||:..|||
  Fly   228 ---------------------YQLKRHI-RQHTGAKPYTCQYCQRNFADRTSLVKHERTHRNERP 270

  Fly   300 YACQHRDKRFAQLGVLKIHERIHTGERLHRCQVCEKPFTRAGQLRKH 346
            |||:...|:|....|||:|.:.||||:.|.||:|.|.|.|...|..|
  Fly   271 YACKTCGKKFTYASVLKMHYKTHTGEKPHICQLCNKSFARIHNLVAH 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7963	NP_649798.3	zf-AD	10..80	CDD:285071	26/91 (29%)
		C2H2 Zn finger	159..179	CDD:275368	3/19 (16%)
		COG5048	184..>250	CDD:227381	18/74 (24%)
		C2H2 Zn finger	189..209	CDD:275368	7/19 (37%)
		C2H2 Zn finger	217..237	CDD:275368	5/19 (26%)
		C2H2 Zn finger	245..262	CDD:275368	2/16 (13%)
		C2H2 Zn finger	274..294	CDD:275368	7/19 (37%)
		C2H2 Zn finger	302..322	CDD:275368	7/19 (37%)
		zf-H2C2_2	315..339	CDD:290200	13/23 (57%)
		C2H2 Zn finger	330..350	CDD:275368	8/17 (47%)
CG4424	NP_650859.3	zf-AD	10..92	CDD:285071	24/80 (30%)
		C2H2 Zn finger	189..209	CDD:275368	7/19 (37%)
		DUF45	<204..281	CDD:302795	33/105 (31%)
		COG5048	210..>345	CDD:227381	48/137 (35%)
		C2H2 Zn finger	217..237	CDD:275368	9/48 (19%)
		C2H2 Zn finger	245..265	CDD:275368	7/19 (37%)
		zf-H2C2_2	257..282	CDD:290200	12/24 (50%)
		C2H2 Zn finger	273..293	CDD:275368	7/19 (37%)
		zf-H2C2_2	286..310	CDD:290200	13/23 (57%)
		C2H2 Zn finger	301..320	CDD:275368	8/17 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	0	0.000