DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7963 and CG17359

DIOPT Version :9

Sequence 1:	NP_649798.3	Gene:	CG7963 / 41001	FlyBaseID:	FBgn0037584	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	NP_648679.1	Gene:	CG17359 / 39549	FlyBaseID:	FBgn0036396	Length:	339	Species:	Drosophila melanogaster

Alignment Length:	358	Identity:	100/358 - (27%)
Similarity:	159/358 - (44%)	Gaps:	52/358 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 CRVCLKQDELLVDIY-------EIVEEMQVDLCTLLETCGGIKVDRRDVQPMYLCQECTNELLIA 67
            ||||..:.:.|:|||       ..|:|.:..|.|:|..|.|..|.:.|..|.::|.||...:..|
  Fly     7 CRVCRDESDCLLDIYTEPYASSNRVQEQEPVLATMLRECSGCSVHKEDGMPQFICVECAEAVRNA 71

  Fly    68 AKFRKICVES----EKLRDMAPEI-NIDTAEPLASEEIIIIDPSDYIEQLSAVEDPE-NEPIGVS 126
            .:.|:.|.:|    |:||.|..|: :|:....:...    |:|...:..:.|.:.|| :||:.|
  Fly    72 YRLRRQCRKSHQYFEQLRLMMKELDDIEYCLNIGDN----IEPQMPVSVMEAGKTPETSEPLLV- 131

  Fly   127 RWNCQHCGAGFQLSEVLRRHIQEVHASITIIDCRERRRIFTKLGCYQVHNCSYAKTPKRGHKCLE 191
                       :|.:|.....:....|..:.|..|.:         ...:.|.||||....|...
  Fly   132 -----------ELVQVKYMPPEPKPISSPLPDNNEHK---------LAQSYSPAKTPHNKSKRRA 176

  Fly   192 CGKCLQSASSLASHIRLHTDEWPFTCDQCAKAFRTNGALEVHQRRHKQVLQHKCLHCGRGFVESS 256
            .......:.|..|.:....|:..:...:..|..|..|             .::|..|.:.|.:..
  Fly   177 RSYSDNDSWSPDSELEHEDDDKIWNASKRGKPKRVPG-------------PYRCKLCTQSFTQKQ 228

  Fly   257 NLRRHIVNRHTEERPHLCNVYQRSFSRVYMLELHLRTNTGERPYACQHRDKRFAQLGVLKIHERI 321
            ||..| :..||.|||:.|::..|||::...|:.|.|.:|||||:.|.:..|||.|:|.|::|.|.
  Fly   229 NLEIH-MRIHTGERPYKCSLCPRSFAQKGNLQSHTRCHTGERPFGCPNCPKRFRQVGQLQVHTRT 292

  Fly   322 HTGERLHRCQVCEKPFTRAGQLRKHALRHETGQ 354
            ||||:..:|..|::.|.:...|:||...|..|:
  Fly   293 HTGEQPFKCSKCQQSFKQLNGLQKHMSAHTRGK 325

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7963	NP_649798.3	zf-AD	10..80	CDD:285071	26/80 (33%)
		C2H2 Zn finger	159..179	CDD:275368	1/19 (5%)
		COG5048	184..>250	CDD:227381	9/65 (14%)
		C2H2 Zn finger	189..209	CDD:275368	2/19 (11%)
		C2H2 Zn finger	217..237	CDD:275368	3/19 (16%)
		C2H2 Zn finger	245..262	CDD:275368	5/16 (31%)
		C2H2 Zn finger	274..294	CDD:275368	7/19 (37%)
		C2H2 Zn finger	302..322	CDD:275368	9/19 (47%)
		zf-H2C2_2	315..339	CDD:290200	10/23 (43%)
		C2H2 Zn finger	330..350	CDD:275368	6/19 (32%)
CG17359	NP_648679.1	zf-AD	6..88	CDD:285071	26/80 (33%)
		zf-C2H2	215..237	CDD:278523	6/22 (27%)
		C2H2 Zn finger	217..237	CDD:275368	6/20 (30%)
		zf-H2C2_2	229..254	CDD:290200	12/25 (48%)
		C2H2 Zn finger	245..265	CDD:275368	7/19 (37%)
		zf-H2C2_2	257..282	CDD:290200	12/24 (50%)
		C2H2 Zn finger	273..293	CDD:275368	9/19 (47%)
		zf-H2C2_2	286..310	CDD:290200	10/23 (43%)
		C2H2 Zn finger	301..321	CDD:275368	6/19 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910