DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7963 and CG10321

DIOPT Version :9

Sequence 1:	NP_649798.3	Gene:	CG7963 / 41001	FlyBaseID:	FBgn0037584	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	NP_001261124.1	Gene:	CG10321 / 37464	FlyBaseID:	FBgn0034643	Length:	855	Species:	Drosophila melanogaster

Alignment Length:	281	Identity:	60/281 - (21%)
Similarity:	104/281 - (37%)	Gaps:	52/281 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 GIKVDRRDVQPMYLCQECTNELLIAAKFRKICVESEKLRDMAPEINIDTAEPLASEEIIIIDPSD 107
            |:.::..|.||. .....|:..|.||..|::...:..:.....:.|.:....|.:|
  Fly   557 GVTLEPCDHQPP-AAGSTTSSKLAAANSRQLVQTASVIAAAGADDNYEIDANLVTE--------- 611

  Fly   108 YIEQLSAVEDPENEPIGVSRWNCQHCGAGFQLSEVLRRHIQEVHASITIIDCRERRRIFTKLGCY 172
            :|.|       ...|:|..|:.|..|...|:..:.|:.|   :|:....|..
  Fly   612 FIRQ-------HTSPLGSGRYICHLCSTEFRQFKGLQNH---MHSHTNWIRA------------- 653

  Fly   173 QVHNCSYAKTPKRGHKCLECGKCLQSASSLASHIRLHTDE--WPFTCDQCAKAFRTNGALEVHQR 235
               ||      |:..:|..|.|..:....|..|::.|..|  .|. |..|.:.|::...|..|::
  Fly   654 ---NC------KKQPQCQICLKSFKGPGMLRMHMKTHDAESSTPM-CTICNRTFKSKAILYRHRQ 708

  Fly   236 RHKQVLQHKC--LHCGRGFVESSNLRRHIVNRHTEERPHL--CNVYQRSFSRVYMLELHLRTNTG 296
            .|:| ..:.|  .:|.:.|..:.||:.|:..:|.|....|  |......:..|..|:||:.:...
  Fly   709 THQQ-RAYCCGVANCRKNFSSAVNLKWHVERKHPEVVDPLFKCGECGSLYDNVDSLQLHVESTDH 772

  Fly   297 ERPYACQHRDKRFAQLGVLKI 317
            ........:|..|:  |.:.|
  Fly   773 SAEVQISGQDDAFS--GAVSI 791

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7963	NP_649798.3	zf-AD	10..80	CDD:285071	9/36 (25%)
		C2H2 Zn finger	159..179	CDD:275368	2/19 (11%)
		COG5048	184..>250	CDD:227381	18/69 (26%)
		C2H2 Zn finger	189..209	CDD:275368	5/19 (26%)
		C2H2 Zn finger	217..237	CDD:275368	5/19 (26%)
		C2H2 Zn finger	245..262	CDD:275368	5/18 (28%)
		C2H2 Zn finger	274..294	CDD:275368	5/19 (26%)
		C2H2 Zn finger	302..322	CDD:275368	4/16 (25%)
		zf-H2C2_2	315..339	CDD:290200	1/3 (33%)
		C2H2 Zn finger	330..350	CDD:275368
CG10321	NP_001261124.1	zf-AD	12..80	CDD:214871
		ASF1_hist_chap	<405..516	CDD:304562
		C2H2 Zn finger	627..647	CDD:275368	6/22 (27%)
		C2H2 Zn finger	661..681	CDD:275368	5/19 (26%)
		C2H2 Zn finger	690..710	CDD:275368	5/19 (26%)
		C2H2 Zn finger	717..740	CDD:275368	6/22 (27%)
		C2H2 Zn finger	750..767	CDD:275368	4/16 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	0	0.000