Protein Alignment CG7963 and Prdm9

DIOPT Version :10

• Sequence 1: NP_649798.3
• Gene: CG7963 / 41001
• FlyBaseID: FBgn0037584
• Length: 339
• Species: Drosophila melanogaster
• Sequence 2: NP_001102373.2
• Gene: Prdm9 / 365155
• RGDID: 1305247
• Length: 796
• Species: Rattus norvegicus
• Alignment Length: 285
• Identity: 93/285 - (32%)
• Similarity: 131/285 - (45%)
• Gaps: 8/285 - (2%)

  Fly    72 KICVESEKLRDMAPEINIDTAEPLASEEIIIIDP--SDYIEQLSAVEDPENEPIGVSRWNCQHCG 134
            |..||.|........|. |||:...:.|...|:.  .......|.|.:.:....|...:.|:.||
  Rat   489 KRTVEEELRTGQTTNIE-DTAKSFIASETSRIERQCGQCFSDKSNVSEHQRTHTGEKPYICRECG 552

  Fly   135 AGFQLSEVLRRHIQEVHASITIIDCRERRRIFTKLGCYQVHNCSYAKTPKRGHKCLECGKCLQSA 199
            .||.....|.:| |..|.......|||..|.||:......|..::  |.::.:.|.|||:.....
  Rat   553 RGFSQKSDLIKH-QRTHTEEKPYICRECGRGFTQKSDLIKHQRTH--TEEKPYICRECGRGFTQK 614

  Fly   200 SSLASHIRLHTDEWPFTCDQCAKAFRTNGALEVHQRRHKQVLQHKCLHCGRGFVESSNLRRHIVN 264
            |.|..|.|.||.|.|:.|.:|.:.|.....|..|||.|.:...:.|..|||||.:.|:|.|| ..
  Rat   615 SDLIKHQRTHTGEKPYICRECGRGFTQKSDLIKHQRTHTEEKPYICRECGRGFTQKSSLIRH-QR 678

  Fly   265 RHTEERPHLCNVYQRSFSRVYMLELHLRTNTGERPYACQHRDKRFAQLGVLKIHERIHTGERLHR 329
            .||.|:|::|......|::...|..||||:|||:||.|:.....|.:...|..|:|.||||:.:.
  Rat   679 THTGEKPYICRECGLGFTQKSNLIRHLRTHTGEKPYICRECGLGFTRKSNLIQHQRTHTGEKPYI 743

  Fly   330 CQVCEKPFTRAGQLRKHALRHETGQ 354
            |:.|.:..|....|.:|...| ||:
  Rat   744 CRECGQGLTWKSSLIQHQRTH-TGE 767

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7963	NP_649798.3	zf-AD	10..80	CDD:462262	4/7 (57%)
		C2H2 Zn finger	159..179	CDD:275368	7/19 (37%)
		COG5048	184..>250	CDD:227381	22/65 (34%)
		C2H2 Zn finger	189..209	CDD:275368	8/19 (42%)
		C2H2 Zn finger	217..237	CDD:275368	7/19 (37%)
		C2H2 Zn finger	245..262	CDD:275368	9/16 (56%)
		C2H2 Zn finger	274..294	CDD:275368	6/19 (32%)
		C2H2 Zn finger	302..322	CDD:275368	5/19 (26%)
		C2H2 Zn finger	330..350	CDD:275368	5/19 (26%)
Prdm9	NP_001102373.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..23
		KRAB	32..89	CDD:214630
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	149..172
		SSXRD	175..205	CDD:430657
		PR-SET_PRDM7_9	244..372	CDD:380970
		COG5048	402..748	CDD:227381	86/263 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	443..497		4/7 (57%)
		C2H2 Zn finger	521..540	CDD:275368	2/18 (11%)
		C2H2 Zn finger	548..568	CDD:275368	8/20 (40%)
		C2H2 Zn finger	576..596	CDD:275368	7/19 (37%)
		C2H2 Zn finger	604..624	CDD:275368	8/19 (42%)
		C2H2 Zn finger	632..652	CDD:275368	7/19 (37%)
		C2H2 Zn finger	660..680	CDD:275368	10/20 (50%)
		C2H2 Zn finger	688..708	CDD:275368	6/19 (32%)
		C2H2 Zn finger	716..736	CDD:275368	5/19 (26%)
		C2H2 Zn finger	744..764	CDD:275368	5/19 (26%)
		zf-H2C2_2	756..780	CDD:463886	5/13 (38%)
		C2H2 Zn finger	772..792	CDD:275368