DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9684 and smyd1b

DIOPT Version :9

Sequence 1:	NP_649797.2	Gene:	CG9684 / 41000	FlyBaseID:	FBgn0037583	Length:	642	Species:	Drosophila melanogaster
Sequence 2:	NP_001034725.1	Gene:	smyd1b / 569027	ZFINID:	ZDB-GENE-060522-1	Length:	486	Species:	Danio rerio

Alignment Length:	519	Identity:	107/519 - (20%)
Similarity:	171/519 - (32%)	Gaps:	133/519 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 AQAKGKCVHCANAAERVCQRCGDF----YCSKHCQRQDWLRHRYICIPLPALVSPNEYSVFQSDR 74
            :||...|..|....|:: ||||..    ||.|.|||..|..|:..|..:.....|...:|
Zfish    41 SQASSICHSCFRRQEKL-QRCGQCRFAQYCDKTCQRAGWEEHKLECAAIKTYGKPPSENV----- 99

  Fly    75 ESTLEGACSLNADKSVVEASPIPLSRSPILPDLQCNNAGRSSIIAAKDDIP-------------- 125
              .|........||.....|...|:....|.|..|:        .::||:.
Zfish   100 --RLAARILWRMDKQGSVVSDNQLTTLEDLEDHICD--------ISEDDLKDFKVDIHNFLDYWP 154

  Fly   126 -VSPPKAIIPPSGAMVYITDFISSNRCYIRDASESAERAFDEVCKKVNTIATLLPRIKNPPPNRL 189
             .|.|..:    .::.:|...|:.|...:.|     :|....|.      ..|.|        .|
Zfish   155 RNSKPHTV----DSVSHILGVINCNGFMVSD-----QRGLQAVG------VGLFP--------NL 196

  Fly   190 CLVHFNGMYVRAKMCKKLREVSHLFLVDLGIKHSGPFFDFKDINDELKALPCSSQLVQLKNVLNC 254
            |||:.:..    ..|..:....:...:|. :.||.     |.|  ||:||...|...:: .|...
Zfish   197 CLVNHDCW----PNCTVILNNGNQSAIDT-VFHSQ-----KRI--ELRALGKISAGEEV-TVAYV 248

  Fly   255 DYSNDVIAFNSKFVGKKYMATIKKCPGLHLVELVNTEMNFS---------VNEQLNAF--FNSKK 308
            ||.| |.|...:.:.::|..   .|...|..|.:..::..:         ..||:...  |:.:|
Zfish   249 DYLN-VSADRQRLLKQQYFF---DCTCKHCTEKIKDDLKMAGAEVDGVKVPEEQVKEVTEFSRQK 309

  Fly   309 LLR--------NPNSAAENIKSCSLEGPQPSHIDQPIAIPAIEC--KKMLTKPEVQNECEEILKQ 363
            |.:        |.|...:..:.| :|..:....|..|....:.|  .::|:..:..:|..|..::
Zfish   310 LEKMEKARIEANYNEVVKICREC-VEKQENVLADTHIYYLRVCCTLSEVLSYLQFFDEASEYARK 373

  Fly   364 QNSGQIDQSKSTN-----VLVTEGASNKMLGFIDLAD----KATK----TDQDTAPKPKDEDVKH 415
            ...|.:......|     ..:..|.::...|||::|.    ||..    |...|.|..||.:...
Zfish   374 MVDGYLKLYHPNNAQLGMATMRAGVTHWQAGFIEVAHGMICKAFAILMITHGPTHPITKDLEAMR 438

  Fly   416 SLTQCLTPKANYPLQLPNHKKNLELPVIHKTNAQTNGIVMSKNEHVLKPPFEMRRFSIESKEGI 479
            ..|:                  :||.:..    |...:..|..|..||.. .||..:..:.|||
Zfish   439 MQTE------------------MELRMFQ----QNEYVYHSMREAALKNQ-PMRMMAEPTNEGI 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9684	NP_649797.2	zf-MYND	20..55	CDD:280009	15/38 (39%)
		TUDOR	132..250	CDD:278965	23/117 (20%)
		TUDOR	527..574	CDD:119391
smyd1b	NP_001034725.1	zf-MYND	47..85	CDD:280009	15/38 (39%)
smyd1b	NP_001034725.1	SET	<173..247	CDD:214614	22/105 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	1	0.960